Protein Oxidation and Aging (eBook)

Tilman Grune, Betul Catalgol, Tobias Jung, Vladimir Uversky (Autoren)

eBook Download: PDF

2012 | 1. Auflage
516 Seiten
John Wiley & Sons (Verlag)
978-1-118-49299-4 (ISBN)

Infos

Reviews our current understanding of the role of protein
oxidation in aging and age-related diseases

Protein oxidation is at the core of the aging process. Setting
forth a variety of new methods and approaches, this book helps
researchers conveniently by exploring the aging process and
developing more effective therapies to prevent or treat age-related
diseases. There have been many studies dedicated to the
relationship between protein oxidation and age-related pathology;
now it is possible for researchers and readers to learn new
techniques as utilizing protein oxidation products as biomarkers
for aging.

Protein Oxidation and Aging begins with a description of
the tremendous variety of protein oxidation products. Furthermore,
it covers:

* Major aspects of the protein oxidation process

* Cellular mechanisms for managing oxidized proteins

* Role of protein oxidation in aging

* Influence of genetic and environmental factors on protein
oxidation

* Measuring protein oxidation in the aging process

* Protein oxidation in age-related diseases

References at the end of each chapter serve as a gateway to the
growing body of original research studies and reviews in the
field.

Autor

TILMAN GRUNE, MD, is Full Professor and Director of the Institute of Nutrition at Friedrich Schiller University Jena. His research examines the biological phenomenon of oxidative stress. In particular, his research group has been investigating the oxidative stress response of cells and organisms and the protective influence of antioxidants. BETUL CATALGOL, MD, is Assistant Professor in the Faculty of Medicine and the Department of Biochemistry at Marmara University. She is coauthor of Proteasome and Neurodegenerative Diseases, Proteasome and Cancer, and Protein Carbonyl Measurement by Enzyme-Linked Immunosorbent Assay. TOBIAS JUNG, PhD, is a Research Assistant at Friedrich Schiller University Jena. He is coauthor of Structure of the Proteasome.

Rezensionen

"With its discussion of current concepts linked to protein
oxidation and its impact on aging and the pathology of certain
age-related diseases, this book is an important contribution to the
field. Students, researchers, scientists, and even clinicians will
benefit from it." (Doody's, 10 January
2013)

"The format and compartmentalised writing style make this
an excellent compendium of knowledge for any researcher interested
in assessing our state of knowledge of protein oxidation and
ageing. It is easy to find out about the current state of knowledge
about a specific reaction, product, method, and/or disease and
follow this up by accessing the extensive list of
references." (Chemistry & Industry, 1 July
2013)

Produkt-Details

• Erscheint lt. Verlag: 7.11.2012
• Reihe/Serie: Wiley Series in Protein and Peptide Science
• Reihe/Serie: Wiley Series in Protein and Peptide Science
• Sprache: englisch
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Histologie / Embryologie
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
• Themenwelt: Naturwissenschaften ► Chemie ► Organische Chemie
• Themenwelt: Technik
• Schlagworte: Biowissenschaften • Cell & Molecular Biology • Chemie • Chemistry • Life Sciences • Medical Science • Medizin • Pharmacology & Pharmaceutical Medicine • Pharmakologie u. Pharmazeutische Medizin • Proteinchemie • Proteine • Protein Science • Zell- u. Molekularbiologie
• ISBN-10: 1-118-49299-4 / 1118492994
• ISBN-13: 978-1-118-49299-4 / 9781118492994