Statistical Methods in Diagnostic Medicine (eBook)
John Wiley & Sons (Verlag)
978-0-470-31792-1 (ISBN)
XIAO-HUA ANDREW ZHOU is Associate Professor in the Department of Biostatistics at Indiana University's School of Medicine. NANCY A. OBUCHOWSKI is Associate Staff at the Cleveland Clinic Foundation. DONNA K. McCLISH is Associate Professor of Biostatistics at Virginia Commonwealth University's Medical College of Virginia.
Preface.
Acknowledgments.
1. Introduction.
1.1 Why This Book?
1.2 What Is Diagnostic Accuracy?
1.3 Landmarks in Statistical Methods for Diagnostic Medicine.
1.4 Software.
1.5 Topics not Covered in This Book.
1.6 Summary.
I BASIC CONCEPTS AND METHODS.
2. Measures of Diagnostic Accuracy.
2.1 Sensitivity and Specificity.
2.2 The Combined Measures of Sensitivity and Specificity.
2.3 The ROC Curve.
2.4 The Area Under the ROC Curve.
2.5 The Sensitivity at a Fixed FPR.
2.6 The Partial Area Under the ROC Curve.
2.7 Likelihood Ratios.
2.8 Other ROC Curve Indices.
2.9 The Localization and Detection of Multiple Abnormalities.
2.10 Interpretation of Diagnostic Tests.
2.11 Optimal Decision Threshold on the ROC Curve.
2.12 Multiple Tests.
3. The Design of Diagnostic Accuracy Studies.
3.1 Determining the Objective of the Study.
3.2 Identifying the Target-Patient Population.
3.3 Selecting a Sampling Plan for Patients.
3.4 Selecting the Gold Standard.
3.5 Choosing a Measure of Accuracy.
3.6 Identifying the Target-Reader Population.
3.7 Selecting a Sampling Plan for Readers.
3.8 Planning the Data Collection.
3.9 Planning the Data Analyses.
3.10 Determining the Sample Size.
4. Estimation and Hypothesis Testing in a Single Sample.
4.1 Binary-Scale Data.
4.2 Ordinal-Scale Data.
4.3 Continuous-Scale Data.
4.4 Hypothesis Testing About the ROC Area.
5. Comparing the Accuracy of Two Diagnostic Tests.
5.1 Binary-Scale Data.
5.2 Ordinal- and Continuous-Scale Data.
5.3 Tests of Equivalence.
6. Sample Size Calculation.
6.1 The Sample Size for Accuracy Studies of a Single Test.
6.2 The Sample Size for the Accuracy of Two Tests.
6.3 The Sample Size for Equivalent Studies of Two Tests.
6.4 The Sample Size for Determining a Suitable Cutoff Value.
7. Issues in Meta-Analysis for Diagnostic Tests.
7.1 Objectives.
7.2 Retrieval of the Literature.
7.3 Inclusion-Exclusion Criteria.
7.4 Extracting Information From the Literature.
7.5 Statistical Analysis.
7.6 Public Presentation.
II ADVANCED METHODS.
8. Regression Analysis for Independent ROC Data.
8.1 Four Clinical Studies.
8.2 Regression Models for Continuous-Scale Tests.
8.3 Regression Models for Ordinal-Scale Tests.
9. Analysis of Correlated ROC Data.
9.1 Studies With Multiple Test Measurements of the Same Patient.
9.2 Studies With Multiple Readers and Tests.
9.3 Sample Size Calculation for Multireader Studies.
10. Methods for Correcting Verification Bias.
10.1 A Single Binary-Scale Test.
10.2 Correlated Binary-Scale Tests.
10.3 A Single Ordinal-Scale Test.
10.4 Correlated Ordinal-Scale Tests.
11. Methods for Correcting Imperfect Standard Bias.
11.1 One Single Test in a Single Population.
11.2 One Single Test in G Populations.
11.3 Multiple Tests in One Single Population.
11.4 Multiple Binary Tests in G Populations.
12. Statistical Methods for Meta-Analysis.
12.1 Sensitivity and Specificity Pairs.
12.2 ROC Curve Areas.
Index.
"...a comprehensive account of statistical methods for design
and analysis of diagnostic studies..." (Quarterly of
Applied Mathematics, Vol. LXI, No. 2, June 2003)
"The medical value of this...should be apparent to anyone...this
material is not extensively covered in medical statistics
textbooks." (Technometrics, Vol. 45, No. 1, February
2003)
"...the book is a valuable addition to the literature in the
field, serving as a much-needed guide for both clinicians and
advanced students". (Zentralblat MATH, Vol.1007, No.7,
2003)
| Erscheint lt. Verlag | 4.11.2009 |
|---|---|
| Reihe/Serie | Wiley Series in Probability and Statistics |
| Wiley Series in Probability and Statistics | Wiley Series in Probability and Statistics |
| Zusatzinfo | Tables: 106 B&W, 0 Color; Graphs: 37 B&W, 0 Color |
| Sprache | englisch |
| Themenwelt | Mathematik / Informatik ► Mathematik ► Statistik |
| Mathematik / Informatik ► Mathematik ► Wahrscheinlichkeit / Kombinatorik | |
| Studium ► 2. Studienabschnitt (Klinik) ► Anamnese / Körperliche Untersuchung | |
| Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie | |
| Technik | |
| Schlagworte | accuracies • accuracy • Anthropologie • Anthropology • Biological Anthropology • Biologische Anthropologie • Biostatistics • Biostatistik • Book • Comparison • comprehensive account • Design • Diagnostic • Diagnostik • estimation • important • Medical Science • Medicine • Medizin • Research • Role • Sample • Statistical Methods • Statistics • Statistik • Studies • Tests |
| ISBN-10 | 0-470-31792-2 / 0470317922 |
| ISBN-13 | 978-0-470-31792-1 / 9780470317921 |
| Haben Sie eine Frage zum Produkt? |
PDF (Ohne DRM)Digital Rights Management: ohne DRM
Dieses eBook enthält kein DRM oder Kopierschutz. Eine Weitergabe an Dritte ist jedoch rechtlich nicht zulässig, weil Sie beim Kauf nur die Rechte an der persönlichen Nutzung erwerben.
Dateiformat: PDF (Portable Document Format)
Mit einem festen Seitenlayout eignet sich die PDF besonders für Fachbücher mit Spalten, Tabellen und Abbildungen. Eine PDF kann auf fast allen Geräten angezeigt werden, ist aber für kleine Displays (Smartphone, eReader) nur eingeschränkt geeignet.
Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.
Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.
aus dem Bereich
