Tutorials in Biostatistics, Statistical Methods in Clinical Studies (eBook)

Ralph B. D'Agostino (Herausgeber)

eBook Download: PDF

2005 | 1., Volume 1
John Wiley & Sons (Verlag)
978-0-470-02366-2 (ISBN)

Infos

The Tutorials in Biostatistics have become a very popular
feature of the prestigious Wiley journal, Statistics in
Medicine (SIM). The introductory style and practical focus make
them accessible to a wide audience including medical practitioners
with limited statistical knowledge. This book represents the
first of two volumes presenting the best tutorials published in
SIM, focusing on statistical methods in clinical studies. Topics
include the design and analysis of clinical trials, epidemiology,
survival analysis, and data monitoring. Each tutorial is focused on
a medical problem, has been fully peer-reviewed and edited, and is
authored by leading researchers in biostatistics. Many
articles include an appendix on the latest developments since
publication in the journal and additional references.

This will appeal to statisticians working in medical research,
as well as statistically-minded clinicians, biologists,
epidemiologists and geneticists. It will also appeal to graduate
students of biostatistics.

Autor

Ralph D'Agostino, Boston University, USA One of the editors of Statistics in Medicine and editor of the Tutorials in Biostatistics series in the journal.

Inhalt

Preface.

Preface to Volume 1.

Part I: OBSERVATIONAL STUDIES/EPIDEMIOLOGY.

1.1 Epidemiology.

Computing Estimates of Incidence, including Lifetime Risk:
Alzheimer's Disease in the Framingham Study. The Practical
Incidence Estimators (PIE) Macro. (Alexa Beiser et al).

The Applications of Capture-Recapture Models to Epidemiological
Data. (Anne Chao et al).

1.2 Adjustment Methods.

Propensity Score Methods for Bias Reduction in the Comparison of
a Treatment to a Non-Randomized Control Group (Ralph B.
D'Agostino Jr.).

1.3 Agreement Statistics.

Kappa Coefficients in Medical Research (Helen Chmura Kraemer et
al).

1.4 Survival Models.

Survival Analysis in Observational Studies (Kate Bull and David
J. Spiegelhalter).

Methods for Interval-Censored Data (Jane C. Lindsey and Louise
M. Ryan).

Analysis of Binary Outcomes in Longitudinal Studies Using
Weighted Estimating Equations and Discrete-Time Survival Methods:
Prevalence and Incidence of Smoking in an Adolescent Cohort (John
B. Carlin et al).

Part II: PROGNOSTIC/CLINICAL PREDICTION MODELS.

2.1 Prognostic Variables.

Categorizing a Prognostic Variable: Review of Methods, Code for
Easy Implementation and Applications to Decision-Making about
Cancer Treatments (Madhu Mazumdar and Jill R. Glassman).

2.2 Prognostic/Clinical Prediction Models.

Development of Health Risk Appraisal Functions in the Presence
of Multiple Indicators: The Framingham Study Nursing Home
Institutionalization Model (R. B. D'Agostino et al).

Multivariable Prognostic Models: Issues in Developing Models,
Evaluating Assumptions and Adequacy, and Measuring and Reducing
Errors (Frank E. Harrell Jr et al).

Development of a Clinical Prediction Model for an Ordinal
Outcome: The World Health Organization Multicentre Study of
Clinical Signs and Etiological Agents of Pneumonia, Sepsis and
Meningitis in Young Infants (Frank E. Harrell Jr. et al).

Using Observational Data to Estimate Prognosis: An Example Using
a Coronary Artery Disease Registry (Elizabeth R. DeLong et al).

Part III: CLINICAL TRIALS.

3.1 Design.

Designing Studies for Dose Response (Weng Kee Wong and Peter A.
Lachenbruch.).

3.2 Monitoring.

Bayesian Data Monitoring in Clinical Trials (Peter M. Fayers et
al).

3.3 Analysis.

Longitudinal Data Analysis (Repeated Measures) in Clinical
Trials (Paul S. Albert).

Repeated Measures in Clinical Trials: Simple Strategies for
Analysis Using Summary Measures (Stephen Senn et al).

Strategies for Comparing Treatments on a Binary Response with
Multi-Centre Data (Alan Agresti, and Jonathan Hartzel).

A Review of Tests for Detecting a Monotone Dose-Response
Relationship with Ordinal Response Data (Christy Chuang-Stein and
Alan Agresti).

Rezensionen

"The articles within the volume are self-contained, well written,
and accessible to readers of widely ranging backgrounds. These
volumes should be extremely valuable to practitioners..."
(Journal of the American Statistical Association, December
2005)

"The biostatistical practitioners who use a broad range of
statistical methods would definitely find beneficial and useful to
have 'Tutorials in Biostatistics'..." (E-STREAMS,
September 2005)

" ...this book gives a well-written and concise
overview of selected biostatistical subjects."
(Journal of the Royal Statistical Society, Series A, June
2005)

Produkt-Details

• Erscheint lt. Verlag: 27.9.2005
• Sprache: englisch
• Themenwelt: Mathematik / Informatik ► Mathematik ► Statistik
• Themenwelt: Mathematik / Informatik ► Mathematik ► Wahrscheinlichkeit / Kombinatorik
• Themenwelt: Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie
• Themenwelt: Technik
• Schlagworte: accessible • best tutorials • Biostatistics • Biostatistik • Book • Clinical • Design • feature • First • High • Journal • Methods • Popular • quality • represents • selfcontained • series • Statistical • Statistics • Statistik • Studies • Topics • tutorials • two • uniformly • Volumes
• ISBN-10: 0-470-02366-X / 047002366X
• ISBN-13: 978-0-470-02366-2 / 9780470023662