Nicht aus der Schweiz? Besuchen Sie lehmanns.de

Astrovirus Research (eBook)

Essential Ideas, Everyday Impacts, Future Directions

Stacey Schultz-Cherry (Herausgeber)

eBook Download: PDF
2012 | 2013
XIV, 186 Seiten
Springer New York (Verlag)
978-1-4614-4735-1 (ISBN)

Lese- und Medienproben

Astrovirus Research -
Systemvoraussetzungen
149,79 inkl. MwSt
(CHF 146,30)
Der eBook-Verkauf erfolgt durch die Lehmanns Media GmbH (Berlin) zum Preis in Euro inkl. MwSt.
  • Download sofort lieferbar
  • Zahlungsarten anzeigen
Astroviruses were first identified in the feces of children in 1975.  Since then, they have been found in - 3 to 20% of children with diarrhea.  Given that serological studies have demonstrated that up to 90% of children have been exposed to at least one strain of astrovirus by age 9, the prevalence of infection may be much higher.  Supporting this are studies demonstrating that astroviruses can also be isolated in a subset of asymptomatic individuals, suggesting that a proportion of infected individuals shed the virus asymptomatically or for some time after the resolution of other symptoms of infection.  Asymptomatic carriers may be a major reservoir for astroviruses in the environment and could contribute to dissemination of the virus.  Astroviruses are extremely stable in the environment and can be transmitted nosocomially, directly from infected individuals and potentially animals, and through contaminated food and water. Although typically an acute disease, astrovirus infection in premature infants may be associated with the development of necrotizing enterocolitis and in new-onset celiac disease in children.  Immunocompromised children are even more susceptible often developing persistent infections that lead to wasting or even systemic infections associated with fatal encephalitis.   In spite of its importance, little is known about astrovirus pathogenesis, molecular biology, epidemiology, or cell biology.  The goal of this book is to provide the latest and most up-to-date information on this medically important and rapidly evolving group of viruses.  It will include sections on the history of astroviruses and their disease in humans; information on viral replication and immune responses; new information on how astroviruses induce disease including the expression of a viral enterotoxin regulating intestinal epithelial cell tight junctions, the isolation and identification of new astrovirus genotypes in mammals including humans, and astroviruses of veterinary importance.  Finally, the book will also introduce the complexity of astrovirus epidemiology and potential as an important new zoonotic disease, and its role in food-borne disease.  This will be the first book of its kind and will be of great interest to microbiologists, virologists, infectious disease specialists, immunologists, pediatricians, public health and food safety experts, veterinarians, poultry industry specialists, and researchers and clinicians interested in enteritis. ?
Astroviruses were first identified in the feces of children in 1975. Since then, they have been found in ~ 3 to 20% of children with diarrhea. Given that serological studies have demonstrated that up to 90% of children have been exposed to at least one strain of astrovirus by age 9, the prevalence of infection may be much higher. Supporting this are studies demonstrating that astroviruses can also be isolated in a subset of asymptomatic individuals, suggesting that a proportion of infected individuals shed the virus asymptomatically or for some time after the resolution of other symptoms of infection. Asymptomatic carriers may be a major reservoir for astroviruses in the environment and could contribute to dissemination of the virus. Astroviruses are extremely stable in the environment and can be transmitted nosocomially, directly from infected individuals and potentially animals, and through contaminated food and water. Although typically an acute disease, astrovirus infection inpremature infants may be associated with the development of necrotizing enterocolitis and in new-onset celiac disease in children. Immunocompromised children are even more susceptible often developing persistent infections that lead to wasting or even systemic infections associated with fatal encephalitis. In spite of its importance, little is known about astrovirus pathogenesis, molecular biology, epidemiology, or cell biology. The goal of this book is to provide the latest and most up-to-date information on this medically important and rapidly evolving group of viruses. It will include sections on the history of astroviruses and their disease in humans; information on viral replication and immune responses; new information on how astroviruses induce disease including the expression of a viral enterotoxin regulating intestinal epithelial cell tight junctions, the isolation and identification of new astrovirus genotypes in mammals including humans, and astroviruses of veterinaryimportance. Finally, the book will also introduce the complexity of astrovirus epidemiology and potential as an important new zoonotic disease, and its role in food-borne disease. This will be the first book of its kind and will be of great interest to microbiologists, virologists, infectious disease specialists, immunologists, pediatricians, public health and food safety experts, veterinarians, poultry industry specialists, and researchers and clinicians interested in enteritis. ?

Preface.- Epidemiology of Human Astroviruses.- Replication Cycle of Astroviruses.- Astrovirus Structure and Assembly.- Astrovirus Pathogenesis.- Immune Responses.- Astrovirus Taxonomy.- New Human Astroviruses.- Astrovirus Infections in Animal Mammalian Species.- Avian Astroviruses.- Index.

Erscheint lt. Verlag 12.10.2012
Zusatzinfo XIV, 186 p.
Verlagsort New York
Sprache englisch
Themenwelt Medizin / Pharmazie Allgemeines / Lexika
Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Studium Querschnittsbereiche Infektiologie / Immunologie
Naturwissenschaften Biologie Biochemie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Technik
Schlagworte Astrovirus • celiac disease • epidemiology • Infectious Diseases • zoonotic
ISBN-10 1-4614-4735-6 / 1461447356
ISBN-13 978-1-4614-4735-1 / 9781461447351
Haben Sie eine Frage zum Produkt?
PDFPDF (Wasserzeichen)
Größe: 4,8 MB

DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasser­zeichen und ist damit für Sie persona­lisiert. Bei einer missbräuch­lichen Weiter­gabe des eBooks an Dritte ist eine Rück­ver­folgung an die Quelle möglich.

Dateiformat: PDF (Portable Document Format)
Mit einem festen Seiten­layout eignet sich die PDF besonders für Fach­bücher mit Spalten, Tabellen und Abbild­ungen. Eine PDF kann auf fast allen Geräten ange­zeigt werden, ist aber für kleine Displays (Smart­phone, eReader) nur einge­schränkt geeignet.

Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.

Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.

Mehr entdecken
aus dem Bereich
Antibiotika, Virostatika, Antimykotika, Antiparasitäre Wirkstoffe

von Hans-Reinhard Brodt; Achim Hörauf; Michael Kresken …

eBook Download (2023)
Thieme (Verlag)
CHF 159,95