Nicht aus der Schweiz? Besuchen Sie lehmanns.de

Tumor Ablation (eBook)

Effects on Systemic and Local Anti-Tumor Immunity and on Other Tumor-Microenvironment Interactions

Yona Keisari (Herausgeber)

eBook Download: PDF
2012 | 2013
XII, 156 Seiten
Springer Netherland (Verlag)
978-94-007-4694-7 (ISBN)

Lese- und Medienproben

Tumor Ablation -
Systemvoraussetzungen
149,79 inkl. MwSt
(CHF 146,30)
Der eBook-Verkauf erfolgt durch die Lehmanns Media GmbH (Berlin) zum Preis in Euro inkl. MwSt.
  • Download sofort lieferbar
  • Zahlungsarten anzeigen

The growing knowledge on tumor-immune response interactions and on the tumor microenvironment did not translate so far into better control of cancer by anti-tumor vaccination. The percentage of patients who benefited from vaccination strategies is still too small to justify their general use. It is the aim of this book to present an alternative to the conventional approach of developing injected tumor vaccines to activate anti-tumor immunity, which will fight cancer. It is argued that in situ tumor ablation (destruction) that involves tumor antigen release; cross presentation and the release of danger associated molecular patterns (DAMPs) can make the tumor its own cellular vaccine.

Tumor ablation methods using chemicals, radiation, photodynamic therapy, cryoablation, high-temperature, radiofrequency, high intensity focused ultrasound, and electric-based ablation have been developed for focal tumors. In this book experts will deal with two main topics: I. What are the principles of the various ablation modalities, and II. How each method affects the tumor cells and their microenvironment, and how these effects are responsible for the induction of specific anti-tumor immunity.

The aims of this book are thus: 1. Familiarize the readers with various methods of in situ tumor ablation. 2. Review the literature and stimulate comparisons on the efficacy of different ablation methods for the treatment of tumors of different histotypes. 3. Review the literature on the effects of various ablation methods on systemic and local anti tumor immunity and on other manifestations of the interactions of tumors with their microenvironment. 4. Stimulate comparative studies on the immunostimulatory effects of different ablation modalities.


The growing knowledge on tumor-immune response interactions and on the tumor microenvironment did not translate so far into better control of cancer by anti-tumor vaccination. The percentage of patients who benefited from vaccination strategies is still too small to justify their general use. It is the aim of this book to present an alternative to the conventional approach of developing injected tumor vaccines to activate anti-tumor immunity, which will fight cancer. It is argued that in situ tumor ablation (destruction) that involves tumor antigen release; cross presentation and the release of danger associated molecular patterns (DAMPs) can make the tumor its own cellular vaccine. Tumor ablation methods using chemicals, radiation, photodynamic therapy, cryoablation, high-temperature, radiofrequency, high intensity focused ultrasound, and electric-based ablation have been developed for focal tumors. In this book experts will deal with two main topics: I. What are the principles of the various ablation modalities, and II. How each method affects the tumor cells and their microenvironment, and how these effects are responsible for the induction of specific anti-tumor immunity. The aims of this book are thus: 1. Familiarize the readers with various methods of in situ tumor ablation. 2. Review the literature and stimulate comparisons on the efficacy of different ablation methods for the treatment of tumors of different histotypes. 3. Review the literature on the effects of various ablation methods on systemic and local anti tumor immunity and on other manifestations of the interactions of tumors with their microenvironment. 4. Stimulate comparative studies on the immunostimulatory effects of different ablation modalities.

Preface. Chapter 1. Effect of chemotherapy on the tumor microenvironment and anti-tumor immunity. Chapter 2. Hyperthermia, the tumor microenvironment and immunity. Chapter 3. Radiofrequency Ablation in Cancer Therapy: Tuning in to in situ tumor vaccines. Chapter 4. High Intensity Focused Ultrasound (HIFU) Ablation. Chapter 5. The interrelationship between cryoablation the immune Response and the tumor microenvironment: Stimulatory and Suppressive Effects. Chapter 6. In situ tumor ablation with radiation therapy – its effect on the tumor microenvironment and anti-tumor immunity. Chapter 7. Tumor-localized insult delivered by photodynamic therapy and the breakdown of tumor immunotolerance. Chapter 8. Effect of electric based ablation treatments on the tumor microenvironment and anti-tumor immunity. Index. 

Erscheint lt. Verlag 15.8.2012
Reihe/Serie The Tumor Microenvironment
The Tumor Microenvironment
Zusatzinfo XII, 156 p.
Verlagsort Dordrecht
Sprache englisch
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Radiologie
Studium 1. Studienabschnitt (Vorklinik) Biochemie / Molekularbiologie
Studium Querschnittsbereiche Infektiologie / Immunologie
Schlagworte Ablation • Cancer • Cancer Microenvironment • Immunostimulation • immunotherapy • Radiaton Oncology
ISBN-10 94-007-4694-6 / 9400746946
ISBN-13 978-94-007-4694-7 / 9789400746947
Haben Sie eine Frage zum Produkt?
PDFPDF (Wasserzeichen)
Größe: 2,1 MB

DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasser­zeichen und ist damit für Sie persona­lisiert. Bei einer missbräuch­lichen Weiter­gabe des eBooks an Dritte ist eine Rück­ver­folgung an die Quelle möglich.

Dateiformat: PDF (Portable Document Format)
Mit einem festen Seiten­layout eignet sich die PDF besonders für Fach­bücher mit Spalten, Tabellen und Abbild­ungen. Eine PDF kann auf fast allen Geräten ange­zeigt werden, ist aber für kleine Displays (Smart­phone, eReader) nur einge­schränkt geeignet.

Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.

Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.

Mehr entdecken
aus dem Bereich

von Marija Pinto

eBook Download (2023)
Urban & Fischer Verlag - Lehrbücher
CHF 26,35