Hereditary Colorectal Cancer

Miguel A. Rodriguez-Bigas, Raul Cutait, Patrick M. Lynch, Ian Tomlinson, Hans F.A. Vasen (Herausgeber)

Buch | Softcover

630 Seiten

2012
Springer-Verlag New York Inc.
978-1-4614-2662-2 (ISBN)

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Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients.

Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease.

History.- History: Familial Adenomatous Polyposis.- Historical Aspects of Lynch Syndrome.- Basic Sciences and Genetics.- Molecular Genetics of Familial Adenomatous Polyposis.- DNA Mismatch Repair.- Basic Sciences and Genetics: Hamartomatous Polyposis.- Hyperplastic Polyposis Syndrome: Colorectal Cancer Predisposition.- MUTYH-Associated Polyposis.- Polymorphic Variation and Risk of Colorectal Cancer.- Pathology.- The Pathologist and the Phenotype of Hereditary Colorectal Cancer.- Clinical Science: Familial Adenomatous Polyposis.- Genotype Phenotype Correlation in Familial Adenomatous Polyposis.- Surgery for Familial Adenomatous Polyposis.- Duodenal Adenomas in Familial Adenomatous Polyposis.- FAP-Associated Desmoid Tumours.- Attenuated Familial Adenomatous Polyposis: Diagnosis, Management, and Future Prognosis.- Clinical Science: Hereditary Nonpolyposis Colorectal Cancer.- An Overview of the Lynch Syndrome (Hereditary Non-polyposis Colorectal Cancer).- Surgical Management in Lynch Syndrome.- Extracolonic Tumors.- Surveillance.- Clinical Science: MYH Associated Polyposis.- MUTYH-Associated Polyposis.- Clinical Science: Hamartomatous Polyposis.- Peutz–Jeghers Syndrome.- Clinical Aspects of Juvenile Polyposis.- Hereditary Mixed Polyposis Syndrome and Multiple Adenoma Patients.- Clinical Science: Hyperplastics Polyposis.- Hyperplastic Polyposis.- Genetic Counseling.- Genetic Counseling Overview.- Across Culture and Health Systems: Europe.- Across Culture and Health Systems: Asia (Hong Kong).- Across Culture and Health Systems: Asia (Japan).- Across Culture and Health Systems: Africa.- Across Culture and Health Systems: Argentina.- Genetic Counselling Across Culture and Health Systems: Australia.- Across Culture and Health Systems: Korea.- Across Culture and Health Systems: America.- Psychosocial Aspects of Hereditary Colorectal Cancer.- Psychological Impact of Genetic Counseling and Testing for Hereditary Colorectal Cancers.- Chemoprevention.- Chemoprevention for Inherited Colorectal Cancer.- Registries.- Registries.- Erratum.- Erratumto: Chapter 22: Hereditary Mixed Polyposis Syndrome and Multiple Adenoma Patients.

Reihe/Serie	MD Anderson Solid Tumor Oncology Series ; 5
Zusatzinfo	XVIII, 630 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizinische Fachgebiete ► Chirurgie ► Viszeralchirurgie
	Medizinische Fachgebiete ► Innere Medizin ► Gastroenterologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
Schlagworte	Adenomas • Colorectal Cancer • Polyposis • Tumors
ISBN-10	1-4614-2662-6 / 1461426626
ISBN-13	978-1-4614-2662-2 / 9781461426622
Zustand	Neuware