Tamoxifen Concepts & Cancer

New Paradigms

Buch | Hardcover

209 Seiten

2013
Nova Science Publishers Inc (Verlag)
978-1-62081-520-5 (ISBN)

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Tamoxifen was first approved in 1977 and up to now remains a noteworthy therapeutic weapon to treat mainly breast cancer. However, further considerations exist regarding the tamoxifen profile. This book discusses recent research and future perspectives in the tamoxifen field. The topics discussed include tamoxifen pharmacokinetics, pharmacodynamics, adverse effects, clinical indications, therapeutic drug monitoring, autophagy mechanisms, tamoxifen topical formulation and breast cancer risk prevention, the use of tamoxifen in an oestrogen-independent manner for various neoplasms (Hepatocellular carcinoma, renal cell carcinoma, high grade glioma), mechanisms of resistance, potential role of CYP2D6, tamoxifen and antidepressants interaction in a psychiatric view, obesity influence in tamoxifen treatment, electrical pulse-mediated tamoxifen delivery, and tamoxifen in melanoma treatment.

Preface; Introduction to Tamoxifen in Novel Approaches; Tamoxifen Metabolism & Biological Activity; Tamoxifen & Autophagy: To Cease & Resist?; Ecotoxicological Effects of Tamoxifen in the Aquatic Environment; Novel Approaches to Tamoxifen Administration for Breast Cancer Prevention; The Use of Tamoxifen in an Estrogen-Independent Manner for Various Neoplasms.

Verlagsort	New York
Sprache	englisch
Maße	180 x 260 mm
Gewicht	584 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Arbeits- / Sozial- / Umweltmedizin
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Studium ► Querschnittsbereiche ► Klinische Umweltmedizin
ISBN-10	1-62081-520-6 / 1620815206
ISBN-13	978-1-62081-520-5 / 9781620815205
Zustand	Neuware