Immobilized Enzymes in Medicine

Vladimir P. Torchilin (Autor)

Buch | Softcover

VIII, 206 Seiten

2011 | 1. Softcover reprint of the original 1st ed. 1991
Springer Berlin (Verlag)
978-3-642-75823-2 (ISBN)

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The application of immobilized enzymes in medicine is the main objective of this book. The author reviews natural and synthetic carriers for enzyme immobilization, chemistry of enzyme binding, and in-vitro and in-vivo properties of immobilized enzymes. Four chapters are dedicated to clinical use of immobilized enzymes.

1 Introduction.- 2 Enzymes in Medicine: Advantages and Disadvantages.- 2.1 Native Enzymes in Therapy and Clinical Analysis.- 2.2 Difficulties Connected with Enzyme Application in Medicine...- 2.3 How the Immobilization can Help.- 3 Immobilization of Therapeutic Enzymes.- 3.1 General Principles of Enzyme Stabilization and Immobilization.- 3.2 The Peculiarities of Enzyme Immobilization for Medical Use. Carriers and Immobilization Methods Required.- 3.3 The Fate of Immobilized Enzymes in the Body.- 3.4 Principal Types of Immobilized Enzymes in Medicine.- 4 Therapeutic Immobilized Enzymes for Parenteral Application.- 4.1 Preparations Intended for Prolonged Circulation in the Body.- 4.2 Insoluble Immobilized Enzymes for Local Application.- 4.3 Immobilization Principles and Drug Targeting.- 5 Immobilized Enzymes for Extracorporeal Application.- 5.1 Immobilized Enzymes in Extracorporeal Systems.- 5.2 Dressing and Drainage Materials Containing Immobilized Enzymes; Films, Ointments and Powders with Immobilized Enzymes in the Treatment of Wounds, Ulcers and Burns.- 6 Immobilized Enzymes in Clinical Analysis.- 6.1 Enzyme Electrodes.- 6.2 Enzyme Immunoassay.- 6.3 Immobilized Bioluminiscent Systems.- 6.4 Reactors with Immobilized Enzymes; Miscellaneous.- 7 Conclusion.- 8 References.

Erscheint lt. Verlag	13.12.2011
Reihe/Serie	Progress in Clinical Biochemistry and Medicine
Zusatzinfo	VIII, 206 p.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	340 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
Schlagworte	biochemistry • Chemistry • Drug • Enzyme • enzymes • Enzymtherapie • Immobilized Enzymes • Klinische Chemie • Pathobiochemie • Pathobiochemistry
ISBN-10	3-642-75823-1 / 3642758231
ISBN-13	978-3-642-75823-2 / 9783642758232
Zustand	Neuware