Current Topics in Microbiology and Immunology / Ergebnisse der Microbiologie und Immunitätsforschung

W. Arber, W. Henle, P. H. Hofschneider, J. H. Humphrey, N. K. Jerne, P. Koldovský, H. Koprowski, O. Maaløe, R. Rott, H. G. Schweiger, M. Sela, L. Syru?ek, P. K. Vogt (Autoren)

Buch | Softcover

IV, 202 Seiten

2011 | 1. Softcover reprint of the original 1st ed. 1976
Springer Berlin (Verlag)
978-3-642-66532-5 (ISBN)

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Expression of an immune response is the net result of complex synergis tic and antagonistic activities performed by a variety of cell types. It includes macrophages, T and B populations which may interact in performance of a response, and suppressor cells interfering with it. Accordingly, a lack of res ponse may not necessarily indicate absence of immunocompetent cells, but rather nonexpression of competence. Thus, one should consider two possible situations, which are by no means mutually exclusive, to account for immuno logic unresponsiveness: (a) one or more of the cell populations composing the synergistic unit is absent or immature, and (b) an antagonistic unit which interferes with the response is dominating. In view of this, an approach to development of immune reactivity necessitates parallel surveys of development of cells with the potential to perform, as well as of cells which can suppress the response. Classification of the various cell types has been based so far on their phenotypic properties (e. g. , membrane antigen markers, cell receptors, pro duction and secretion of immunoglobulins, etc. ). Genotypically, T and B cells may represent either separate, independent cell lines, or different stages of development within the same cell lineage.

In vitro Approach to Development to Immune Reactivity.- Blocking and Unblocking Serum Factors in Neoplasia.- Bacteriophage T7 Genetics.- IS-Elements in Microorganisms.- Structure and Molecular Biology of Rabies Virus.- Cumulative Author and Subject Index Volumes 40-75.- Indexed in I SR.

Erscheint lt. Verlag	23.11.2011
Reihe/Serie	Current Topics in Microbiology and Immunology
Zusatzinfo	IV, 202 p.
Verlagsort	Berlin
Sprache	englisch
Maße	170 x 244 mm
Gewicht	368 g
Themenwelt	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
Themenwelt	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
Schlagworte	Antigen • Biology • Cell • immune response • Immunität • Immunoglobulin • immunology • Macrophages • Membrane • Microbiology • Population
ISBN-10	3-642-66532-2 / 3642665322
ISBN-13	978-3-642-66532-5 / 9783642665325
Zustand	Neuware