Molecular Genetics and Therapy of Leukemia

Emil J. Freireich, Hagop Kantarjian (Herausgeber)

Buch | Softcover

334 Seiten

2011 | Softcover reprint of the original 1st ed. 1996
Springer-Verlag New York Inc.
978-1-4612-8537-3 (ISBN)

Artikel merken

Leukemia is a malignant disease which continues to play a cutting edge role in the discovery of new basic knowledge about the malignant process and about the potential for controlling these malignant diseases. Molecular Genetics and Therapy of Leukemia presents contributions by leading investigators and scientific contributors to such topics as chromosome 16, chromosome 5, the BCL-2 gene, 11q23 breakpoint leukemias, the p-53 suppressor gene and oncogene, hematopoietic stem cells, cytokines, detection of minimal residual disease in acute lymphoblastic leukemia, autologous marrow transplantation, the retinoblastoma gene, allogeneic bone marrow transplant and chemotherapy of acute lymphoblastic leukemia.

1. Molecular Genetics of Inversion 16 Leukemia: Implications for Leukemogenesis.- 2. Deletion of Chromosome 5 (5q-) in Leukemia: Current Knowledge.- 3. Bcl-2 Family Proteins and the Regulation of Programmed Cell Death in Leukemia and Lymphoma.- 4. MLL Fusion Genes in the 11q23 Acute Leukemias.- 5. The c-myb Protooncogene: A Novel Target for Human Gene Therapy.- 6. The Role of p53 in Malignancy.- 7. Primitive Hematopoietic Stem and Progenitor Cells in Human Umbilical Cord Blood: An Alternative Source of Transplantable Cells.- 8. Detection of Minimal Residual Disease in ALL: Biology, Methods, and Applications.- 9. Interleukin-6: Biologic Properties and Role in Lymphoproliferative Disorders.- 10. Autologous Bone Marrow Transplantation for Leukemia and Lymphoma.- 11. Retinoblastoma Gene in Malignancy.- 12. Treatment of Relapse After Allogeneic Bone Marrow Transplantation.- 13. Acute Lymphocytic Leukemia: A Comprehensive Review with Emphasis on Biology and Therapy.

Reihe/Serie	Cancer Treatment and Research ; 84
Zusatzinfo	XIV, 334 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
ISBN-10	1-4612-8537-2 / 1461285372
ISBN-13	978-1-4612-8537-3 / 9781461285373
Zustand	Neuware