The Genetic Basis of Human Cancer
McGraw-Hill Inc.,US (Verlag)
978-0-07-067596-4 (ISBN)
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Part 1 Basic concepts in genetics: genetics, biochemistry and the molecular basis of variant human phenotypes; the nature and mechanisms of human gene mutation; the Human Genome Project; genetic imprinting in cancer. Part 2 Controls on cell growth: control of the cell cycle; apoptosis and cancer; oncogenes; tumour suppressor genes. Part 3A Inherited mutations - defects in DNA repair: xeroderma pigmentosa; ataxia telangiectasia; Bloom's syndrome; Fanconi anaemia; hereditary non-polyposis colorectal cancer; Werner syndrome. Part 3B defects in growing controlling genes: retinoblastoma; Li-Fraumenni syndrome; Wilms tumour; peripheral neurofibromatosis; central neurofibromatosis; renal carcinoma; multiple endocrine neoplasia; malignant melanoma; breast cancer; colorectal tumours. Part 4 Somatic mutations: chromosome translocations in leukemias and lymphomas; chromosome rearrangements human in solid tumours; gene amplification in human cancers - biological and clinical significance; pancreatic cancer; ovarian cancer; endometrial cancer; cervical cancer; bladder cancer; stomach cancer; prostate cancer; brain tumours; lung cancer; skin cancer; hepatocellular carcinoma; genetic testing for cancer.
| Erscheint lt. Verlag | 1.11.1998 |
|---|---|
| Zusatzinfo | illustrations |
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 221 x 292 mm |
| Gewicht | 1850 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
| ISBN-10 | 0-07-067596-1 / 0070675961 |
| ISBN-13 | 978-0-07-067596-4 / 9780070675964 |
| Zustand | Neuware |
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