Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products, Vol. 92

A. Douglas Kinghorn, Heinz Falk, Junichi Kobayashi (Herausgeber)

Buch | Softcover

XI, 175 Seiten

2012 | 2010
Springer Wien (Verlag)
978-3-7091-1103-1 (ISBN)

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Resin glycosides are part of a very extensive family of secondary metabolites known as glycolipids or lipo-oligosaccharides and are constituents of complex resins (glycoresins) (1) unique to the morning glory family, Convolvulaceae (2). These active principles are responsible for the drastic purgative action of all the important Convolvulaceous species used in traditional medicine throughout the world since ancient times. Several commercial purgative crude drugs can be prepared from the roots of different species of Mexican morning glories. Their incorporation as therapeutic agents in Europe is an outstanding example of the assimilation of botanical drugs from the Americas as substitutes for traditional Old World remedies (3). Even though phytochemical investigations on the constituents of these drugs were initiated during the second half of the nineteenth century, the structure of their active ingredients still remains poorly known for some examples of these purgative roots. During the last two decades, the higher resolution c- abilities of modern analytical isolation techniques used in conjunction with pow- ful spectroscopic methods have facilitated the elucidation of the active principles of these relevant herbal products. This chapter describes the ethnobotanical information associated with the p- gative morning glory species and how traditional usages were instrumental in plant selection for chemical studies. The advantages and limitations of available analy- cal techniques for the isolation, puri?cation, and structure characterization of the individual constituents of these complex glycoconjugates are also discussed.

Herbert Budzikiewicz, geboren 1933 in Wien, Studium der Chemie, 1959 Promotion im Fach Organische Chemie. 1961-65 Senior Research Associate an der Stanford Univ. (USA) mit Aufbau und Leitung der Abteilung für Massenspektrometrie betraut. 1965-1969 an der TU Braunschweig mit Habilitation 1966. 1970 Berufung zum ordentlichen Professor an das Institut für Organische Chemie der Univ. zu Köln, verblieben bis 2002 (Emeritierung). Arbeitsschwerpunkt: Massenspektrometrie und Naturstoffchemie (Untersuchung von Bakterieninhaltsstoffen). Autor bzw. Koautor mehrerer Bücher über die Anwendung der Massenspektrometrie zur Strukturanalyse organischer Verbindungen.

Herbert Budzikiewicz: Microbial SiderophoresRogelio Pereda-Miranda, Daniel Rosas-Ramírez, and Jhon Castañeda-Gómez: Resin Glycosides from the Morning Glory Family

Erscheint lt. Verlag	4.5.2012
Reihe/Serie	Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products
Co-Autor	Herbert Budzikiewicz, Rogelio Pereda-Miranda, Daniel Rosas-Ramírez, Jhon Castañeda-Gómez
Zusatzinfo	XI, 175 p.
Verlagsort	Vienna
Sprache	englisch
Maße	155 x 235 mm
Gewicht	293 g
Themenwelt	Medizin / Pharmazie ► Pharmazie ► PTA / PKA
Themenwelt	Naturwissenschaften ► Chemie ► Organische Chemie
Schlagworte	biochemistry • Chemistry • Coumarinolignans • Flavonolignans • Naturstoffe • non-conventional lignans • picrotoxane • picrotoxin • Polymer • Stilbenolignans
ISBN-10	3-7091-1103-X / 370911103X
ISBN-13	978-3-7091-1103-1 / 9783709111031
Zustand	Neuware