Osteoclasts

Morphology, Functions & Clinical Implications

Alexander J Brown (Autor)

Buch | Hardcover

169 Seiten

2012
Nova Science Publishers Inc (Verlag)
978-1-62081-306-5 (ISBN)

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Osteoclasts are highly specialised cells, derived from the hematopoietic lineage, that resorb mineralised bone matrix. Osteoclast precursors can be recruited to the bone remodelling sites by specific cytokines in the microcellular environment, including some secreted by osteoblasts, fibroblasts, and osteocytes. In this book, the authors present current research in the study of the morphology, functions and clinical implications of osteoclasts. Topics include osteoclast formation and function and its risk in skeletal bone disease; the high osteoclastogenic potential of human osteosarcoma cells; osteoclast biology regarding Paget's disease and p62 mutations; the role of immuno-skeletal interface in the regulation of osteoclast formation; and osteoclasts in patients with neurofibromatosis 1.

Preface; Modulation of Osteoclast Differentiation & Function in Rheumatoid Arthritis; Osteoclasts Formation & Function & Its Risk in Skeletal Bone Disease; The High Osteoclastogenic Potential of Human Oteosarcoma Cells: Reciprocal Interaction between MG63 Osteoblast-Like Cells & Osteoclast Precursors; Osteoclast Biology in Paget's Disease of Bone; Osteoclasts: The Major Actors in Bone Resorption; Role of the Immuno-Skeletal Interface in Physiological & Pathological Osteoclast Regulation; Multiple Functions of Osteoclasts & Potential Usefulness of Phosphatidylserine-Containing Liposomes on Bone Diseases.

Verlagsort	New York
Sprache	englisch
Maße	260 x 180 mm
Gewicht	500 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Orthopädie
ISBN-10	1-62081-306-8 / 1620813068
ISBN-13	978-1-62081-306-5 / 9781620813065
Zustand	Neuware