Irreversible Electroporation
Seiten
2012
|
2010
Springer Berlin (Verlag)
978-3-642-26199-2 (ISBN)
Springer Berlin (Verlag)
978-3-642-26199-2 (ISBN)
Written by leading researchers, this book provides a brief introduction to the emerging field of irreversible electroporation in medicine. A brief historical perspective of irreversible electroporation is presented and recent studies are discussed.
Non-thermal irreversible electroporation is a new minimally invasive surgical p- cedure with unique molecular selectivity attributes - in fact it may be considered the first clinical molecular surgery procedure. Non-thermal irreversible electro- ration is a molecular selective mode of cell ablation that employs brief electrical fields to produce nanoscale defects in the cell membrane, which can lead to cell death, without an effect on any of the other tissue molecules. The electrical fields can be produced through contact by insertion of electrode needles around the undesirable tissue and non-invasively by electromagnetic induction. This new - dition to the medical armamentarium requires the active involvement and is of interest to clinical physicians, medical researchers, mechanical engineers, che- cal engineers, electrical engineers, instrumentation designers, medical companies and many other fields and disciplines that were never exposed in their training to irreversible electroporation or to a similar concept. This edited book is designed to be a comprehensive introduction to the field of irreversible electroporation to those that were not exposed or trained in the field before and can also serve as a reference manual. Irreversible electroporation is broad and interdisciplinary. Therefore, we have made an attempt to cover every one of the various aspects of the field from an introductory basic level to state of the art.
Non-thermal irreversible electroporation is a new minimally invasive surgical p- cedure with unique molecular selectivity attributes - in fact it may be considered the first clinical molecular surgery procedure. Non-thermal irreversible electro- ration is a molecular selective mode of cell ablation that employs brief electrical fields to produce nanoscale defects in the cell membrane, which can lead to cell death, without an effect on any of the other tissue molecules. The electrical fields can be produced through contact by insertion of electrode needles around the undesirable tissue and non-invasively by electromagnetic induction. This new - dition to the medical armamentarium requires the active involvement and is of interest to clinical physicians, medical researchers, mechanical engineers, che- cal engineers, electrical engineers, instrumentation designers, medical companies and many other fields and disciplines that were never exposed in their training to irreversible electroporation or to a similar concept. This edited book is designed to be a comprehensive introduction to the field of irreversible electroporation to those that were not exposed or trained in the field before and can also serve as a reference manual. Irreversible electroporation is broad and interdisciplinary. Therefore, we have made an attempt to cover every one of the various aspects of the field from an introductory basic level to state of the art.
History of IRE.- Basic Bioelectronics.- Review of Experimental Studies on IRE of Cells.- Review of Mathematical Models of IRE of Cells.- Mathematical Models of Heat Transfer during non Thermal IRE of Tissue.- Review of experimental Studies of IRE in Tissue.- Mathematical Models of Anisotropic.- Treatment Planning.- Electrochemotherapy and IRE.- Clinical Results with IRE (prostate).- Clinical Results with IRE (Liver, Kidney, Lung).- IRE Tissue Electroporation Systems.- Food.
| Erscheint lt. Verlag | 14.3.2012 |
|---|---|
| Reihe/Serie | Series in Biomedical Engineering |
| Zusatzinfo | XIV, 313 p. |
| Verlagsort | Berlin |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 497 g |
| Themenwelt | Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie |
| Technik | |
| Schlagworte | cell membrane • Cells • Electrophoresis • IFMBE • irreversible electroporation • oncolog • tissue • tissue ablation |
| ISBN-10 | 3-642-26199-X / 364226199X |
| ISBN-13 | 978-3-642-26199-2 / 9783642261992 |
| Zustand | Neuware |
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