Arsenic Exposure and Health Effects V (eBook)

C.O. Abernathy, R.L. Calderon, W.R. Chappell, D.J. Thomas (Herausgeber)

eBook Download: PDF

2003 | 1. Auflage
554 Seiten
Elsevier Science (Verlag)
978-0-08-052756-7 (ISBN)

Infos

The authoritative articles in this book represent the state-of-the-art in arsenic research. Arsenic experts from around the world - participants in the Fifth International Conference on Arsenic Exposure and Health Effects organized by the Society for Environmental Geochemistry and Health in 2002 - present their critical findings. The authors share their latest arsenic research findings in Occurrence, Epidemiology, Biomarkers and Animal Models, Mode of Action, Mode of Action, Risk Estimation, Intervention and Medical Treatment, and Water Treatment and Remediation.

As in past conferences, the first report of elevated arsenic exposures in a new country was given. The Conference introduced the finding of arsenic contamination in Nepal and updates of the arsenic problems in Bangladesh, India, Vietnam are included.

A vital contribution to arsenic study and policy making, this volume examines the global impact of the toxin and discusses arsenic in the environment, mechanisms of arsenic metabolism and carcinogenesis, water treatment technology, and medical care. Arsenic Exposure and Health Effects V offers informed, challenging insights into a highly important and controversial topic.

Inhalt

Cover 1
Contents 8
Preface 6
List of Contributors 12
PART I: OCCURRENCE AND EXPOSURE 22
Chapter 1. Groundwater Arsenic Exposure in India 24
Chapter 2. Groundwater Arsenic Contamination in Nepal: a new challenge for water supply sector 46
Chapter 3. Environmental Impacts, Exposure Assessment and Health Effects related to Arsenic Emissions from a Coal-Fired Power Plant in Central Slovakia the EXPASCAN Study
Chapter 4. Trivalent Arsenic Species: Analysis, Stability, and Interaction with a Protein 72
Chapter 5. Arsenic in Yellowknife, North West Territories, Canada 90
Chapter 6. Occurrence of Public Health and Environmental Hazards and Potential Remediation of Arsenic-Containing Soils, Sediments, Surface Water and Groundwater at the Lava Cap Mine NPL Superfund Site in Nevada County, California 100
Chapter 7. Investigation of Arsenic Release from Sediment Minerals to Water Phases 114
Chapter 8. Arsenic and Heavy Metal Contamination of Rice, Pulses and Vegetables Grown in Samta Village, Bangladesh 124
PART II: EPIDEMIOLOGY 136
Chapter 9. Criteria for Case Definition of Arsenicosis 138
Chapter 10. Arsenic Exposure Alters Purine Metabolism in Rats, Mice, and Humans 156
Chapter 11. Risk Analysis of Non-Melanoma Skin Cancer Incidence in Arsenic Exposed Population 168
Chapter 12. Effect of Arsenic-Contaminated Drinking Water on Skin Cancer Prevalence in Wisconsin’s Fox River Valley 176
PART III: BIOMARKERS AND ANIMAL MODELS 186
Chapter 13. Alteration of GSH Level, Gene Expression and Cell Transformation in NIH3T3 Cells by Chronic Exposure to Low Dose of Arsenic 188
Chapter 14. Laboratory and Field Evaluation of Potential Arsenic Exposure from Mine Tailings to Grazing Cattle 202
Chapter 15. Does Arsenic Require a Carcinogenic Partner? 218
Chapter 16. Carcinogenicity of Dimethylarsinic Acid and Relevant Mechanisms 232
PART IV: MODE OF ACTION 244
Chapter 17. Enzymology and Toxicity of Inorganic Arsenic 246
Chapter 18. Structural Proteomics of Arsenic Transport and Detoxification 262
Chapter 19. A Novel S-adenosylmethionine-dependent Methyltransferase from Rat Liver Cytosol Catalyzes the Formation of Methylated Arsenicals 276
Chapter 20. Metabolism of Arsenic and Gene Transcription Regulation: Mechanism of AP-1 Activation by Methylated Trivalent Arsenicals 288
Chapter 21. Effect of Antioxidants on the Papilloma Response and Liver Glutathione Modulation Mediated by Arsenic in Tg.AC Transgenic Mice 304
Chapter 22. Application of Filter Arrays to the Study of Arsenic Toxicity and Carcinogenesis 316
Chapter 23. Regulation of Redox and DNA Repair Genes by Arsenic: Low Dose Protection Against Oxidative Stress?. 326
Chapter 24. Carcinogenicity of Dimethylarsinic Acid (DMAV) 342
Chapter 25. Urinary Speciation of Sodium Arsenate in Folate Receptor Knockout Mice 358
Chapter 26. Some Chemical Properties Underlying Arsenic’s Biological Activity 366
Chapter 27. Arsenic Metabolism in Hyperbilirubinemic Rats: Distribution and Excretion in Relation to Transformation 376
Chapter 28. Incorporating Mechanistic Insights in a PBPK Model for Arsenic 390
PART V: INTERVENTION AND MEDICAL TREATMENT 400
Chapter 29. Natural History Following Arsenic Exposure: A Study in an Arsenic Endemic Area of West Bengal, India 402
Chapter 30. Saha’s Grading of Arsenicosis Progression and Treatment 412
Chapter 31. Painting Tube Wells Red or Green Alone Does Not Help Arsenicosis Patients 436
Chapter 32. Arsenic Mitigation in Bangladesh 442
Chapter 33. Normative Role of WHO in Mitigating Health Impacts of Chronic Arsenic Exposure in the South-East Asia Region 460
PART VI: WATER TREATMENT AND REMEDIATION 470
Chapter 34. Arsenic SolutionsŽ Web Platform of > 50 Options for Developing Countries: Collaborative Design and Innovation for the Common Good
Chapter 35. Investigation of Arsenic Removal Technologies for Drinking Water in Vietnam 480
Chapter 36. Removing Arsenic from Drinking Water: A Brief Review of Some Lessons Learned and Gaps arisen in Chilean Water Utilities 492
Chapter 37. Disposal of Wastes Resulting from Arsenic Removal Processes 504
Chapter 38. Development of a Low-waste Technology for Arsenic Removal from Drinking Water 512
Part VII: AN OVERVIEW OF SOME US EPA AND NIEHS PROGRAMS ON ARSENIC 524
Chapter 39. An Update on Some Arsenic Programs at the US EPA 526
Subject Index 542

Produkt-Details

• Erscheint lt. Verlag: 19.12.2003
• Sprache: englisch
• Themenwelt: Schulbuch / Wörterbuch ► Lexikon / Chroniken
• Themenwelt: Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie
• Themenwelt: Studium ► Querschnittsbereiche ► Prävention / Gesundheitsförderung
• Themenwelt: Naturwissenschaften ► Chemie
• Themenwelt: Naturwissenschaften ► Geowissenschaften ► Geologie
• Themenwelt: Technik
• Themenwelt: Wirtschaft
• ISBN-10: 0-08-052756-6 / 0080527566
• ISBN-13: 978-0-08-052756-7 / 9780080527567