Ion Pumps, Part A (eBook)
248 Seiten
Elsevier Science (Verlag)
978-0-08-087707-5 (ISBN)
Both eukaryotic and prokaryotic cells depend strongly on the function of ion pumps present in their membranes. The term ion pump, synonymous with active ion-transport system, refers to a membrane-associated protein that translocates ions uphill against an electrochemical potential gradient. Primary ion pumps utilize energy derived from chemical reactions or from the absorption of light, while secondary ion pumps derive the energy for uphill movement of one ionic species from the downhill movement of another species.
In the present volume, various aspects of ion pump structure, mechanism, and regulation are treated using mostly the ion-transporting ATPases as examples. One chapter has been devoted to a secondary ion pump, the Na+-Ca2+ exchanger, not only because of the vital role played by this transport system in regulation of cardiac contractility, but also because it exemplifies the interesting mechanistic and structural similarities between primary and secondary pumps.
Both eukaryotic and prokaryotic cells depend strongly on the function of ion pumps present in their membranes. The term ion pump, synonymous with active ion-transport system, refers to a membrane-associated protein that translocates ions uphill against an electrochemical potential gradient. Primary ion pumps utilize energy derived from chemical reactions or from the absorption of light, while secondary ion pumps derive the energy for uphill movement of one ionic species from the downhill movement of another species. In the present volume, various aspects of ion pump structure, mechanism, and regulation are treated using mostly the ion-transporting ATPases as examples. One chapter has been devoted to a secondary ion pump, the Na+-Ca2+ exchanger, not only because of the vital role played by this transport system in regulation of cardiac contractility, but also because it exemplifies the interesting mechanistic and structural similarities between primary and secondary pumps.
Cover 1
Advances in Molecular and Cell Biology: Ion Pumps 4
Copyright Page 5
TOC$CONTENTS (Volume 23A) 6
LIST OF CONTRIBUTORS 10
Preface 14
Section I 18
CH$CHAPTER 1. REACTION MECHANISM OF THE SARCOPLASMIC RECTICULUM Ca2+ -ATPASE 18
CH$CHAPTER 2. THE ATP BINDING SITES OF P-TYPE ION TRANSPORT ATPASES: PROPERTIES, STRUCTURE, CONFORMATIONS, AND MECHANISM OF ENERGY COUPLING 50
CH$CHAPTER 3. THE GASTRIC H+-K+-ATPASE 118
CH$CHAPTER 4. GENETIC APPROACHES TO STRUCTURE-FUNCTION ANALYSIS IN THE YEAST PLASMA MEMBRANE H+ -ATPASE 160
CH$CHAPTER 5. COPPER HOMEOSTASIS BY CPX-TYPE ATPASES: THE NEW SUBCLASS OF HEAVY METAL P-TYPE ATPASES 184
CH$CHAPTER 6. ISOSFORM DIVERSITY AND REGULATION OF ORGAN ELLAR-TYPE Ca2+ -TRANSPORT ATPASES 222
Section II 266
CH$CHAPTER 1. COMPARISON OF ATP-POWERED Ca2+ PUMPS 266
CH$CHAPTER 2. MOLECULAR MECHANISMS INVOLVED IN THE REGULATIN OF Na-K-ATPase EXPRESSION 292
CH$CHAPTER 3. STRUCTURE, MECHANISM, AND REGULATION OF THE CARDIAC SARCOLEMMA Na+-Ca2+ EXCHANGER 328
CH$CHAPTER 4. STRUCTURE AND DYNAMICS OF THE F1F0-TYPE ATPASE 376
CH$CHAPTER 5. STRUCTURE AND MECHANISM OF F-TYPE ATPASES 398
CH$CHAPTER 6. STRUCTURE, FUNCTION, AND REGULATION OF THE VACUOLAR (H+)-ATPASES 420
CH$CHAPTER 7. ANION TRANSPORT SYSTEMS 472
IDX$Index 508
| Erscheint lt. Verlag | 19.11.1997 |
|---|---|
| Sprache | englisch |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Hämatologie |
| Naturwissenschaften ► Biologie ► Biochemie | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| Naturwissenschaften ► Physik / Astronomie ► Angewandte Physik | |
| Technik | |
| ISBN-10 | 0-08-087707-9 / 0080877079 |
| ISBN-13 | 978-0-08-087707-5 / 9780080877075 |
| Haben Sie eine Frage zum Produkt? |
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