Phagocytosis: Microbial Invasion (eBook)
380 Seiten
Elsevier Science (Verlag)
978-0-08-052608-9 (ISBN)
This field of study is growing rapidly after a somewhat slow start over recent decades. This collection of invited chapters attempts to reflect current research and brings together cell biologists, microbiologists, and immunologists wiht disthemes, hopefully like a symphony rather than a boring catalogue. It will be evident that editorial bias favors intracellular parasitism and medically important organisms. The neutrophil is far more than a supporting player to the macrophage and some attempt is made to remind the reader of some of its unique skills. To retain a manageable size, the emphasis is on relatively early events such as mutual recognition, cell entry, and response, rather than on longterm changes in gene expression by either host cell or pahtogen. Viruses are excluded not because of lack of importance but because of somewhat different research approaches, although it is becoming increasingly clear that large viruses (e.g. Vaccinia) and Listeria monocytogenes, share common strategies in invasion and intercellular spread.
The present volume focuses on microbial invasion strategies of pathogen uptake. An accompanying volume (Vol. 5) in the series presents the phagocytic process from the viewpiont of the host cell. This field of study is growing rapidly after a somewhat slow start over recent decades. This collection of invited chapters attempts to reflect current research and brings together cell biologists, microbiologists, and immunologists wiht disthemes, hopefully like a symphony rather than a boring catalogue. It will be evident that editorial bias favors intracellular parasitism and medically important organisms. The neutrophil is far more than a supporting player to the macrophage and some attempt is made to remind the reader of some of its unique skills. To retain a manageable size, the emphasis is on relatively early events such as mutual recognition, cell entry, and response, rather than on longterm changes in gene expression by either host cell or pahtogen. Viruses are excluded not because of lack of importance but because of somewhat different research approaches, although it is becoming increasingly clear that large viruses (e.g. Vaccinia) and Listeria monocytogenes, share common strategies in invasion and intercellular spread.
Cover 1
CONTENTS 6
LIST OF CONTRIBUTORS 10
INTRODUCTION TO THE SERIES 16
PREFACE 18
CHAPTER 1. PATHOGEN STRATEGIES: A HITCHIKER'S GUIDE TO THE MACROPHAGE 22
CHAPTER 2. ANTIPHAGOCYTOSIS BY YERSINIA: A MECHANISM INVOLVING PTPAsE-MEDIATED DISRUPTION OF HOST-CELL FOCAL COMPLEXES 48
CHAPTER 3. INVASION OF MAMMALIAN CELLS BY LISTERIA MONOCYTOGENES 80
CHAPTER 4. THE ROLE OF COMPLEMENT RECEPTOR TYPE 3 IN THE INVASION STRATEGIES OF MYCOBACTERIUM TUBERCULOSIS 102
CHAPTER 5. MYCOBACTERIA AND THE ENDOCYTIC PATHWAY 128
CHAPTER 6. LEGIONELLA PNEUMOPHILA AND MYCOBACTERIUM TUBERCULOSIS: TWO PATHWAYS THROUGH THE MONONUCLEAR PHAGOCYTE 158
CHAPTER 7. PHAGOCYTOSIS OF PSEUDOMONAS AERUGINOSA 180
CHAPTER 8. INTERACTION OF SALMONELLA SPP WITH HOST CELLS 194
CHAPTER 9. SHIGELIA HOST CELL INVASION: SIGNIFICANCE IN PATHOGENESIS 202
CHAPTER 10. BRUCELLA ABORTUS INVASION AND SURVIVAL WITHIN PROFESSIONAL AND NONPROFESSIONAL PHAGOCYTES 222
CHAPTER 11. EN ROUTE TO THE VACUOLE: TRACING THE SECRETORY PATHWAY OF TOXOPLASMA GONDII 254
CHAPTER 12. ACTIVE CELL INVASION BY TOXOPLASMA GONDll LEADS TO AVOIDANCE OF PHAGOCYTIC PROCESSING 284
CHAPTER 13. REGULATED EXOCYTOSIS OF LYSOSOMES: A NOVEL PATHWAY REVEALED BY THE INTERACTION OF TRYPANOSOMA CRUZI WITH HOST CELLS 302
CHAPTER 14. PHAGOCYTOSIS OF LEISHMANIA: INTERACTION WITH THE HOST AND INTRACELLULAR TRAFFICKING 318
CHAPTER 15. CELLULAR MECHANISMS OF PHAGOCYTOSIS OF CANDIDA BY MURINE MACROPHAGES 338
CHAPTER 16. NONOPSONIC FIMH-MEDIATED PHAGOCYTOSIS OF E. COLI AND ITS POSSIBLE CONTRIBUTION TO RECURRENT URINARY TRACT INFECTIONS 354
CHAPTER 17. CELL CO-INFECTIONS WITH NONVIRAL PATHOGENS AND THE CONSTRUCTION OF DOUBLY INFECTED PHAGOSOMES 370
INDEX 394
| Erscheint lt. Verlag | 27.1.2000 |
|---|---|
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Mikrobiologie / Infektologie / Reisemedizin |
| Studium ► Querschnittsbereiche ► Infektiologie / Immunologie | |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie | |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| Technik | |
| ISBN-10 | 0-08-052608-X / 008052608X |
| ISBN-13 | 978-0-08-052608-9 / 9780080526089 |
| Haben Sie eine Frage zum Produkt? |
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