Growth and Lactogenic Hormones (eBook)

L. Matera, R. Rapaport (Herausgeber)

eBook Download: PDF

2002 | 1. Auflage
330 Seiten
Elsevier Science (Verlag)
978-0-08-050766-8 (ISBN)

Infos

For more than seventy years evidence has accumulated documenting the existence of a bi-directional communication network between growth hormone and the immune system. In the past twenty years there has been a tremendous proliferation of information detailing the workings of the growth hormone and insulin-like growth factor axis. A multitude of growth factors and binding proteins have been identified. More and more evidence supporting the important role of the growth hormone IGF network in the well functioning of the normal immune system has been documented. Clearly the challenge today is not to prove, but to understand, the neuroimmune regulatory role of GLH in its entire complexity.

The ultimate goal of this volume and of all the other volumes of this series is to promote the understanding of the science and to ease human suffering.

Inhalt

Cover 1
Contents 20
Foreword: The Neuroimmune Biology of Growth and Lactogenic Hormones 6
Preface 16
List of Corresponding Authors 18
Part I: Introduction 24
Chapter 1. Immunoregulation by Prolactin – An Introduction 26
Part II: GLH Biology, Development & Receptors
Chapter 2. The Growth Hormone – Insulin-Like Growth Factor – I Axis and Immunity 32
Chapter 3. Reciprocal Interactions between the GH/IGF-1 System and Cytokines 50
Chapter 4. Biological Significance of Insulin-Like Growth Factor Binding Proteins 60
Chapter 5. The Expression and Function of GH/IGF-I Receptors in the Immune System 90
Chapter 6. Growth Hormone and Insulin-Like Growth Factor-1 Production by Cells of the Immune System 110
Chapter 7. Potential Applications of Growth Hormone in Promoting Immune Reconstitution 124
Chapter 8. Signal Transduction by PRL Receptors 134
Chapter 9. Signal Transduction and Modulation of Gene Expression by Prolactin in Human Leukocytes 146
Chapter 10. Regulation of PRL Release by Ccytokines and Immunomodifiers: Interrelationship between leptin and Prolactin secretion. Functional Implications 160
Chapter 11. Prolactin Expression in the Immune Cells 170
Part III: Hemopiesis and development 184
Chapter 12. Prolactin as a Promoter of Growth and Differentiation of Hemopoietic Cells 186
Chapter 13. Growth Hormone/Insulin-like Growth Factors and Hematopoiesis 200
Chapter 14. Uteroplacental Prolactin Family: Immunological Regulators of Viviparity 210
Part IV: GLH and the immune response 226
Chapter 15. Effect of Prolactin on Natural Killer and MHC-restricted Cytotoxic Cells 228
Chapter 16. In Vivo Changes of PRL Levels During the T-cell Dependent Immune Response 242
Chapter 17. Prolactin regulates Macrophage and NK Cell Mediated Inflammation and Cytotoxic Response Against Tumor 250
Part V: GLH and disease 268
Chapter 18. Acromegaly and Immune Function 270
Chapter 19. Growth Hormone and Insulin-Like Growth Factor-1 in Human Immunodeficiency Virus Infection 282
Chapter 20. Human Prolactin as an Immunohematopoietic Factor: Implications for the Clinic 298
Chapter 21. Effectiveness of Bromocriptine in the Treatment of Autoimmune Diseases 310
Chapter 22. The Pathogenic Role of Prolactin in Patients with Rheumatoid Arthritis 320
Keyword index 328

Produkt-Details

• Erscheint lt. Verlag: 18.4.2002
• Sprache: englisch
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Histologie / Embryologie
• ISBN-10: 0-08-050766-2 / 0080507662
• ISBN-13: 978-0-08-050766-8 / 9780080507668