Methods of Cancer Diagnosis, Therapy and Prognosis (eBook)

Gastrointestinal Cancer

M. A. Hayat (Herausgeber)

eBook Download: PDF

2008 | 2009
XXXI, 247 Seiten
Springer Netherland (Verlag)
978-1-4020-8900-8 (ISBN)

Infos

Each year, tens of millions of people are respectively. The following data indicate diagnosed worldwide with cancer, and the burden (seriousness) of gastrointestinal more than half of these patients eventu- cancer, liver cancer, and colorectal cancers ally die from this disease. The severity of globally and in the United States. (Table 1) the burden of cancer becomes really clear Surgical and molecular therapies and pr- by knowing that there were ? 10, 862, 496 nostic markers for gastrointestinal stromal new cancer cases (excluding skin cancer) tumors are discussed in this volume. Role in the world in 2002, and the number of of anticancer drugs and monoclonal an- deaths caused by this disease in the same bodies specific for these tumors are also year was ? 6,723,887 (GLOBOCAN). discussed. Imaging modality assessing the The number of deaths due to cancer in the effect of anticancer imatinib on these tumors United States was estimated to be 559, 650 is included. Diagnostic and prognostic (Am. Cancer Soc. ). Cancer is caused by markers of clinical outcomes using che- both external factors (tobacco, chemicals, therapy and hormone replacement therapy radiation, and infectious organisms) and for gastric adenocarcinoma are detailed. internal factors (inherited mutations, hor- Also, are discussed immunohistochem- mones, immune conditions, and mutations try of esophageal cancer progression, and that occur from metabolism). diagnostic and therapeutic methodologies All cancer types caused by cigarette for biliary tumors.

Inhalt

PART I: GASTROINTESTINAL CANCERS 1. INTRODUCTION : GASTROINTESTINAL CANCERS M.A. Hayat GASTROINTESTINAL STROMAL TUMORS (GISTs)
GASTRIC CANCER
ESOPHAGEAL CANCER
TREATMENTS
REFERENCES 2. METASTATIC GASTROINTESTINAL CANCER: SAFETY OF CISPLATIN COMBINED WITH CONTINUOUS 5- FLUOROURACIL VERSUS BOLUS 5- FLUOROURACIL AND LEUCOVORIN (METHODOLOGY) Jacqueline Duffour, Oliver Bouche, Philippe Rougier, Chantal Milan, Laurent Bedenne, Jean-Francois Seitz, Bruno Buecher, Jean-Lois Legoux, Michel Ducreux, Denis Vetter, Jean-Luc Raoul, Eric Francois, and Marc Ychou INTRODUCTION
PATIENTS AND METHODS
RESULTS
DISCUSSION
REFERENCES 3. GASTROINTESTINAL CANCER: ENDOSCOPIC SUBMUCOSAL DISSECTION (METHODOLOGY) Atsushi Imagawa INTRODUCTION
INDICATIONS
METHOD AND DISCUSSION
Setting of a High-Frequency Generator
Complications
Esophageal and Colorectal Lesions
REFERENCES 4. GASTROINTESTINAL EPITHELIAL NEOPLASMS: ENDOSCOPIC SUBMUCOSAL DISSECTION (METHODOLOGY) Mitsuhiro Fujishiro INTRODUCTION
APPLICATION
ENDOSCOPIC SYSTEMS AND EQUIPMENT
PROCEDURE
Marking Around the Lesion
Submucosal Injection
Bleeding
Perforation
Management After Endoscopic Submucosal Dissection
FURTHER CONSIDERATIONS
REFERENCES 5. INOPERABLE ABDOMINO-PELVIC TUMORS: TREATMENT WITH RADIOFREQUENCY ABLATION AND SURGICAL DEBULKING Nathan W. Pearlman INTRODUCTION
TECHNIQUE
PATIENT POPULATION AND RESULTS
REFERENCES 6. GASTROINTESTINAL NEUROENDOCRINE TUMORS: DIAGNOSIS USING GASTRIN RECEPTOR SCINTIGRAPHY Martin Gotthardt, Thomas M. Behr, and Martin Béhé NEUROENDOCRINE TUMORS
Symptoms, Clinical Appearance, Therapy, and Prognosis
Diagnostic Imaging Procedures
Potential Improvement of Scintigraphic Imaging of NET by Using
Alternative Radiopeptides
RADIOPEPTIDE SCANNING VERSUS ANATOMICAL IMAGING
MODALITIES
RADIOLABELED PEPTIDES: DEVELOPMENT, ADVANTAGES AND SHORTCOMINGS
MINIGASTRIN FOR DETECTING METASTASIZED NEUROENDOCRINE TUMORS
Cholecystokinine 2 (CCK2) Receptor Expression
Labeling
Scanning Protocol
Biodistribution of MG
Clinical Imaging in Neuroendocrine Tumors
FUTURE PERSPECTIVES OF DGlu1-MINIGASTRIN
REFERENCES PART II: ESOPHAGEAL CANCER 7. DISTAL ESOPHAGUS: EVALUATION OF 18F-FLUORODEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY/ COMPUTED TOMOGRAPHY FUSION IMAGING Domenico Rubello and Cristina Nanni INTRODUCTION
18F-FDG-PET AND PET/CT IN ESOPHAGEAL CANCER
Positivity Criteria
Staging
Disease Relapse
NEOADJUVANT THERAPY RESPONSE
18F-FDG-PET/CT VERSUS OTHER TECHNIQUES
PET/CT AND OTHER RADIOTRACERS
REFERENCES 8. ENDOSCOPIC ULTRASOUND AND STAGING OF ESOPHAGEAL CANCER Kanwar R.S. Gill and Timothy Woodward OBJECTIVES
BASIC PRINCIPLES
EQUIPMENT
PROCEDURE AND TNM CLASSIFICATION
ROLE OF ENDOSCOPIC ULTRASOUND-FINE NEEDLE ASPIRATION
IN ESOPHAGEAL CANCER
ENDOSCOPIC ULTRASOUND IN ASSESSING PRIMARY TUMOR (T STAGING)
ENDOSCOPIC ULTRASOUND IN ASSESSING NODAL METASTASIS
ENDOSCOPIC ULTRASOUND IN ASSESSING DISTANCE METASTASIS
RESTAGING OF ESOPHAGEAL CANCER AFTER CHEMORADIATION
ENDOSCOPIC ULTRASOUND-FINE-NEEDLE ASPIRATION MOLECULAR DIAGNOSIS OF ESOPHAGEAL CANCER
COMPLICATIONS AND SAFETY
REFERENCES 9. ESOPHAGEAL CANCER: ROLE OF RNASEN PROTEIN AND MICRO-RNA IN PROGNOSIS Hideyuki Ishiguro, Yoshiyuki Kuwabara, Nobuyoshi Sugito, and Yoshitaka Fujii INTRODUCTION
REAL-TIME REVERSE TRANSCRIPTION ANALYSIS USING TaqMan PROBES
Isolation of RNA from Tumor Samples and Reverse Transcription Reaction
Real-Time Polymerase Chain Reaction Using TaqMan Probes
IMMUNOHISTOCHEMISTRY OF RNASEN
REFERENCES 10. ESOPHAGEAL CANCER: INITIAL STAGING Lana Y. Schumacher, Nicole B. Baril, and Sherry M. Wren

Produkt-Details

• Erscheint lt. Verlag: 21.12.2008
• Reihe/Serie: Methods of Cancer Diagnosis, Therapy and Prognosis
• Reihe/Serie: Methods of Cancer Diagnosis, Therapy and Prognosis
• Zusatzinfo: XXXI, 247 p.
• Verlagsort: Dordrecht
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Chirurgie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
• Themenwelt: Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren ► Radiologie
• Themenwelt: Medizin / Pharmazie ► Pflege
• Themenwelt: Medizin / Pharmazie ► Studium
• Schlagworte: biopsy • carcinoma • classification • Computed tomography (CT) • Diagnosis • Endoscopy • Image Analysis • Imaging • neuroendocrine tumor • PET/CT • Positron Emission Tomography • Radiaton Oncology • Staging • surgical oncology • TNM staging system • Tumor • Ultrasound
• ISBN-10: 1-4020-8900-7 / 1402089007
• ISBN-13: 978-1-4020-8900-8 / 9781402089008