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Surgical Treatment of Hilar and Intrahepatic Cholangiocarcinoma (eBook)

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2007 | 2008
XIII, 241 Seiten
Springer Italia (Verlag)
978-88-470-0729-1 (ISBN)

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Surgical Treatment of Hilar and Intrahepatic Cholangiocarcinoma -
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This book contains an up-to-date review of diagnostic and staging tools of cholangiocarcinoma, a guide to optimal selection of therapeutic modalities and a review of long-term outcome of surgery and liver transplantation. It also provides surgical techniques and principles for curative and palliative surgery. This book will appeal to physicians and hepatobiliary surgeons who want to improve their knowledge about surgical management of intrahepatic and hilar cholangiocarcinomas.


Cholangiocarcinoma is the second most frequent primary neoplasm of the liver and its incidence is increasing in Western countries. These neoplasms arise from the biliary tract and can be categorized according to their anatomical location as intrahepatic and extrahepatic cholangiocarcinomas. The prognosis of these neoplasms is poor and most patients are not suitable for curative resection at the time of diagnosis ,due to advanced stage of tumor. Complete surgical resection still remains the only effective and potentially curative therapy. Both intrahepatic and hilar cholangiocarcinoma often requires major liver resection to obtain a radical treatment. In recent years the improvements in non- invasive diagnostic imaging modalities, a better understanding of liver anatomy, the improvements of preoperative optimisation of liver function (preoperative biliary drainage, portal vein embolization), the increased safety of liver surgery have gradually improved the outcome. Moreover, aggressive surgical approach could increase curative surgery. Still now the role of adjunvant therapies and liver transplantation are not well clarified.This book contains an up-to-date review of diagnostic and staging tools of cholangiocarcinoma, a guide to optimal selection of therapeutic modalities and a review of long-term outcome of surgery and liver transplantation. Moreover, it provides details of surgical techniques and principles for curative and palliative surgery. This book will appeal to physicians and hepatobiliary surgeons who want to improve their knowledge about surgical management of intrahepatic and hilar cholangiocarcinomas.

Foreword 5
Preface 7
Contents 9
Part 1 Hilar Cholangiocarcinoma 14
Reporting Cholangiocarcinoma: Pathological Aspects 15
Diagnosis 28
Preoperative Staging 39
The Role of Laparoscopy in Preoperative Staging 52
Preoperative Assessment of Liver Function 57
Preoperative Biliary Drainage 64
Preoperative Portal Vein Embolization 73
Prognostic Factors 81
Staging Systems 92
Surgical Anatomy of the Hepatic Hilus 106
Surgical Treatment 117
Surgical Technique 132
Results of Surgery 155
The Role of Liver Transplantation 165
Adjuvant and Neoadjuvant Therapies 171
Palliative Treatments 176
Part 2 Intrahepatic Cholangiocarcinoma 186
Diagnosis 187
Prognostic Factors 193
Staging Systems 203
Surgical Treatment 212
Results of Surgery 220
The Role of Liver Transplantation 228
Adjuvant and Palliative Treatments 232
Subject Index 237

Erscheint lt. Verlag 21.11.2007
Reihe/Serie Updates in Surgery
Updates in Surgery
Mitarbeit Sonstige Mitarbeit: ^L. Marchiori, S. Pachera, L. Bortolasi, R. Manfredi, P. Capelli
Zusatzinfo XIII, 241 p.
Verlagsort Milano
Sprache englisch
Themenwelt Medizinische Fachgebiete Chirurgie Viszeralchirurgie
Medizin / Pharmazie Medizinische Fachgebiete Innere Medizin
Medizin / Pharmazie Pflege
Schlagworte abdominal surgery • anatomy • carcinoma • Cholangiocarcinoma • diagnostic imaging • Hepatobiliary Surgery • hepatology • hilar cholangiocarcinoma • Imaging • Laparoscopy • Liver • liver disease • liver transplantation • Staging • Surgery • Transplantation • Tumor
ISBN-10 88-470-0729-1 / 8847007291
ISBN-13 978-88-470-0729-1 / 9788847007291
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