Cytokines in the Genesis and Treatment of Cancer (eBook)

Michael A. Caligiuri, Michael T. Lotze (Herausgeber)

eBook Download: PDF

2007 | 2007
XIX, 482 Seiten
Humana Press (Verlag)
978-1-59745-455-1 (ISBN)

Infos

Cytokines in the Genesis and Treatment of Cancer provides a comprehensive picture of the dual role of host responses in promoting and inhibiting tumor progression. This volume represents an important investigation into the emerging intersection of cancer biology and cancer immunology. The book brings together an impressive array of internationally distinguished investigators who are devoted to the study of cytokines and cancer.

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Cytokines in the Genesis and Treatment of Cancer provides a comprehensive picture of the dual role of host responses in promoting and inhibiting tumor progression. This volume represents an important investigation into the emerging intersection of cancer biology and cancer immunology. Divided into four sections, the volume's first three parts focus on cytokines in the genesis of cancer. The final section describes the notable progress - both in animal models and humans - in demonstrating the use of cytokine or anticytokine therapies for the prevention and treatment of cancer. Cytokines in the Genesis and Treatment of Cancer brings together an impressive array of internationally distinguished investigators who are devoted to the study of cytokines and cancer. Together, they produce an insightful, comprehensive discussion of cytokines and cancer that will serve as the perfect reference for all those working in the field.

Inhalt

Cytokines in the Genesis and Treatment of Cancer

Co-Editors: Michael A. Caligiuri and Michael T. Lotze



Introduction



1. Overview and Introduction to Cancer and Inflammation

Michael A. Caligiuri and Michael T. Lotze



Part I. Cytokines in the Genesis of Cancer



Infectious Agents, Cytokines and Cancer



2. Helicobacter Pylori

Richard M. Peek, Jr.



3. HTLV-1

Michael Lairmore and Lee Ratner



4. Herpes Viruses

Frank J. Jenkins and Heather R. Hensler



Cytokines and Carcinogenesis



5. TNF

Mark DeWitte, David J. Shealy, Marian Nakada, and G. Mark Anderson



6. TGF-Š

Alyssa R. Bonine, Brian K. Law and Harold L. Moses



7. Interleukin 1 (IL-1) Family of Cytokines

Michael T. Lotze



8. IL-4/13

Koji Kawakami and Raj Puri



9. IL-6 and Castleman's disease

Norihiro Nishimoto



10. Interleukin 10 (IL-10) Family of Cytokines

Shin-ichiro Fujii and Michael Lotze



11. Cytokines in Multiple Myeloma: Therapeutic Implications

Dharminder Chauhan, Teru Hideshima and Kenneth Anderson



12. Murine Cytokine Models and the Genesis of Cancer

Todd A. Fehniger, Megan A. Cooper, Michael A. Caligiuri



13. Experimental Models of Cytokines and Cancer Prevention

Mark J. Smyth, Erika Cretney, Shayna E.A. Street and Yoshihiro Hayakawa



Cytokines and Tumor Stroma/Metastasis



14. Cytokines in the Tumor Stroma

Michael C. Ostrowski



15. Cytokines and Angiogenesis in Tumors

Sharmila Roy-Chowdhury and Charles K. Brown



16. Chemokines and Receptor Expression in Tumor Progression

Paola Allavena, Federica Marchesi and Alberto Mantovani



17. The Biology of Cancer Cachexia: Role of TNF±

Denis Guttridge



Part II: Cytokines in The Treatment Of Cancer



18. IL-2

Kim Margolin and JoeClark



19. IL-12

Timothy E. Bael and Jared Gollob



20. The Type I Interferon Family

Stergios J. Moschos, Gregory B. Lesinski, William E. Carson, III, and John M. Kirkwood



21. Combination Cytokine Therapy

Seth Cohen and Howard Kaufman



22. Novel Strategies for Targeting Cytokine Administration

Paul M. Sondel, Jackie Hank, Mark Albertini and Stephen D. Gilles



23. Cytokines and Cancer Vaccines

Hideho Okada and Michael T. Lotze



24. Anti-cytokine Therapy

Miguel A. Villalona-Calero



25. Cytokines in the Supportive Care of Cancer

John A. Glaspy

Produkt-Details

• Erscheint lt. Verlag: 19.9.2007
• Reihe/Serie: Cancer Drug Discovery and Development
• Reihe/Serie: Cancer Drug Discovery and Development
• Zusatzinfo: XIX, 482 p.
• Verlagsort: Totowa
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
• Themenwelt: Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren ► Radiologie
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• Schlagworte: angiogenesis • Biology • Cancer • cancer prevention • Carcinogenesis • Chemokine • Cytokine • cytokines • Helicobacter pylori • inflammation • Interferon • prevention • Radiaton Oncology • Tumor • tumor progression • Vaccine
• ISBN-10: 1-59745-455-9 / 1597454559
• ISBN-13: 978-1-59745-455-1 / 9781597454551