Insulin Resistance (eBook)

Childhood Precursors and Adult Disease

Philip Scott Zeitler, Kristen J. Nadeau (Herausgeber)

eBook Download: PDF

2008 | 2008
XI, 331 Seiten
Humana Press (Verlag)
978-1-59745-192-5 (ISBN)

Infos

In the mid 1990s, Drs. Gerald Reaven identified a constellation of clinical findings, known variously as the metabolic syndrome, syndrome X, insulin resistance s- drome or insulin resistance-related disorders, that are associated with an increased risk of heart disease and diabetes. Interest in this topic grew rapidly, culminating in the publication by this series of the book, Insulin Resistance and the Metabolic Syndrome X, edited by Drs. Reaven and Laws in 1999. Since the original publication of that now classic volume, the world's population has continued to become more obese and sedentary and the prevalence of disorders related to insulin resistance has continued to increase throughout the developed and developing world. Of great concern in the last decade is the extension of these deleterious lifestyle patterns to the pediatric population, leading to both obesity and the appearance of insulin resistance-related disorders in youth as well as adults. Today, about one in three children and adolescents in the United States is overweight or obese, and this prevalence approaches one in two among adolescents in certain minority groups. In addition, components of this cardiovascular risk constellation are now being recognized in young adults, adolescents, and even children. Youth are increasingly developing type 2 diabetes, fatty liver disease, hypertriglyceridemia, hypertension, polycystic ovarian syndrome, sleep apnea, orthopedic and psychiatric complications, as well as other complications of obesity and insulin resistance.

Inhalt

Epidemiology


The metabolic syndrome: definitions, controversies, and clinical utility. Lewis W Johnson MD, Ruth S Weinstock MD, PhD


Epidemiology of the Metabolic syndrome and related disorders in children and adolescents – Jennifer L Foltz MD, Stephen R Cook MD, MPH


Metabolic syndrome in children and adolescents worldwide – Orit Pinhas-Hamiel MD


Maternal-fetal contributors to the insulin resistance syndrome in youth – Dana Dabelea MD, PhD


Early childhood contributions to insulin resistance – David B Dunger MD, FRCP, FRCPCH, Burak Salgin, Ken K Ong MRCPCH PhD



Pathophysiology




Molecular Mechanisms of insulin resistance - Boris Draznin MD, PhD


Techniques used to assess insulin action – Michael J Pagliassotti PhD, Kyle T. Pfaffenbach MS, Tracy J. Horton


Adiposity is the enemy: body composition and insulin sensitivity – J Higgins PhD, William T Donahoo MD


Ectopic fat deposition: adiponectin and insulin resistance in obese adolescents – Anna MG Cali MD, Sonia Caprio MD


Mediators of insulin resistance - Rocio Periera MD, David Maahs MD


Insulin resistance and the pathogenesis of cardiovascular disease. – Ramzi Ajjan MRCP, MMed.Sci, PhD, Mark T Kearn FRCP, PhD, Peter T Grant FRCP, MD


Insulin Resistance and Cardiovascular disease: Cecilia C Low Wang MD


The liver and insulin resistance: the important convergence of endocrinology and hepatology – Charissa Y Chang, MD , Kerry Whitt MD, Zhenqi Liu MD, Stephen H Caldwell MD


Polycystic Ovarian Syndrome and metabolic syndrome: Marie-Helene. Pesant MD, Jean-Patrice BaillargeonMD




Treatment




Effects of Exercise in Metabolic Syndrome and Diabetes: A Central Role for Insulin Sensitivity – Irene E Schauer MD, PhD, Judith.G. Regensteiner PhD, Jane EB. Reusch MD


Weight loss medications and the metabolic syndrome – Linda Buckley MD, Daniel Bessessen MD.

Produkt-Details

• Erscheint lt. Verlag: 28.12.2008
• Reihe/Serie: Contemporary Endocrinology
• Reihe/Serie: Contemporary Endocrinology
• Zusatzinfo: XI, 331 p.
• Verlagsort: Totowa
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Allgemeinmedizin
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Diabetologie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pädiatrie
• Themenwelt: Medizin / Pharmazie ► Pflege
• Schlagworte: Cardiovascular • Diabetes • Heart disease • Insulin • insulin resistance • Insulin resistance-related disorders • Metabolic Syndrome • Syndrome X
• ISBN-10: 1-59745-192-4 / 1597451924
• ISBN-13: 978-1-59745-192-5 / 9781597451925