Cardiovascular Genomics (eBook)

Mohan K. Raizada, Julian F. R. Paton, Michael J. Katovich, Sergey Kasparov (Herausgeber)

eBook Download: PDF

2008 | 2005
XIV, 362 Seiten
Humana Press (Verlag)
978-1-59259-883-0 (ISBN)

Infos

Recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac dysfunction to stroke and hypertension. The methods described for identifying the genes that cause susceptibility to cardiovascular diseases emphasize the possibility of discovering new drug targets. Authoritative and ground-breaking, Cardiovascular Genomics offers an unprecedented examination of both the cutting-edge scientific approaches now possible and the results obtained from them in the new science of cardiovascular genomics.

Inhalt

Part I. Genes and Polymorphisms in Cardiovascular Disease

Angiotensin II Receptor Polymorphisms and Hypertension
Bruno Baudin

Angiotensinogen Gene Polymorphisms and Hypertension
Ashok Kumar

Substitution Mapping: Using Congenic Strains to Detect Genes Controlling Blood Pressure
Bina Joe and Michael R. Garrett

Local Production of Angiotensinogen: Insights From Genetic Manipulation of Mice
Kamal Rahmouni and Curt D. Sigmund

Cardiovascular Pharmacogenomics
Julie A. Johnson and Larisa H. Cavallari

Genetic Polymorphisms and Response to HMG-CoA Reductase Inhibitors
Anke-Hilse Maitland-van der Zee, Olaf H. Klungel, and Anthonius de Boer

Monogenic Causes of Heart Failure: Familial Dilated Cardiomyopathy
Hideko Kasahara

Part II. Gene Transfer for Combating Cardiovascular Disease

Gene Therapy vs Pharmacotherapy
Ryuichi Morishita

Molecular Therapeutic Approaches for Myocardial Protection
Alok S. Pachori, Luis G. Melo, and Victor J. Dzau

Gene Transfer and the Cardiovascular System
William H. Miller, Stuart A. Nicklin, Andrew H. Baker, and Anna F. Dominiczak

Kallikrein Gene Transfer in Hypertension, Cardiovascular and Renal Disease, and Stroke
Julie Chao and Lee Chao

Current and Future Novel Targets of Gene Therapy for Hypertension
Michael J. Katovich, Justin L. Grobe, and Mohan K. Raizada

Application of Viral Gene Transfer in Studies of Neurogenic Hypertension
Sergey Kasparov, A. G. Teschemacher, and Julian F. R. Paton

Vigilant Vectors: Intelligent Gene Vectors for Cardioprotection in Myocardial Ischemia
M. Ian Phillips and Yi Tang

Gene Therapy for Cerebral Arterial Diseases
Yoshimasa Watanabe and Donald D. Heistad

Part III. Regenerative Tissues for the Diseased Cardiovascular System

Therapeutic Angiogenesis and Vasculogenesis for Tissue Regeneration
Paolo Madeddu

Cell Transplantation: The New Frontier
Shafie Fazel, Paul W. M. Fedak, Richard D. Weisel, Denis Angoulvant, Terrence M. Yau, and Ren-Ke Li

Embryonic Stem Cells and the Cardiovascular System
Neta Lavon and Nissim Benvenisty

Index

Produkt-Details

• Erscheint lt. Verlag: 24.2.2008
• Reihe/Serie: Contemporary Cardiology
• Reihe/Serie: Contemporary Cardiology
• Zusatzinfo: XIV, 362 p.
• Verlagsort: Totowa
• Sprache: englisch
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie
• Themenwelt: Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
• Schlagworte: Angiotensin II • Cardiovascular • genes • gene therapy • Hypertension
• ISBN-10: 1-59259-883-8 / 1592598838
• ISBN-13: 978-1-59259-883-0 / 9781592598830