Pancreatic Disease (eBook)

Protocols and Clinical Research

Colin D. Johnson, Clement W. Imrie (Herausgeber)

eBook Download: PDF

2010 | 2010
XI, 125 Seiten
Springer London (Verlag)
978-1-84882-118-7 (ISBN)

Infos

Clem Imrie and Colin Johnson This book stems from an unusual meeting held in The Royal College of Physicians and Surgeons of Glasgow in March 2007. Enthusiastic doctors in the diagnosis and treatment of pancreatic diseases were arranged in small groups to discuss specific unsolved/partially clinical problems and suggest the way forward. In some instances, the recommendations were initial improved longitudinal studies, while in others better double-blind randomized st- ies. The recommendations were then presented on the second day before the total 40 plus participants who added their input. Finally, the mechanics of initiating the proposals were arranged. The editors are most thankful to the authors from the meeting, who have ass- bled the various contributions to this stimulating volume. xi Part I Potential Trials in Acute Pancreatitis Chapter 1 Acute Pancreatitis in Intensive Care John Kinsella, Barry Clements, Euan Dickson, Thierry Dugernier, and Martin Hughes 1.1 Intr oduction Severe acute pancreatitis is associated with the development of the systemic inflammatory response syndrome (SIRS). Hypoxemia is a hallmark of acute pancreatitis and respiratory failure is the most common single organ failure in this disease. In the most severely ill patients mul- organ dysfunction syndrome (MODS) and multi-organ failure (MOF) occur. Intensive care with multiple organ support is necessary.

Colin Johnson

Reader in Surgery, University of Southampton, Southampton, Hampshire, UK

Clem Imrie

Professor of Surgery, Glasgow Royal Infirmary, Glasgow, UK

Inhalt

Contents 5
Contributors 7
Introduction 10
Potential Trials in Acute Pancreatitis 11
Acute Pancreatitis in Intensive Care 12
Antibiotic Prophylaxis in Acute Severe Pancreatitis: Should We Have a Further Study? 19
Designing an Optimal Study for the Management of Infected Pancreatic Necrosis 28
Nutrition in Acute Pancreatitis 38
An Optimal Randomized Study for Pain Control in Acute Pancreatitis 48
Potential Trials in Chronic Pancreatitis 57
Endoscopic Versus Surgical Drainage for Chronic Pancreatitis 58
Duodenum-Preserving Pancreatic Resection with Pancreatic Duct Drainage: What Is the Role of Supraduodenal Biliary Drainage? 72
Potential Trials in Pancreatic Cancer 76
Pain Management and Nutritional Support in Nonresectable Pancreatic Cancer 77
Endoscopic Therapy in the Palliation of Nonresectable Pancreatic Cancer 82
Pancreatic Endocrine Tumors 87
The Role of the Systemic Inflammatory Response in Predicting Outcome in Patients with Pancreatic Cancer 99
Topic Reviews 105
Botulinum Toxin and the Sphincter of Oddi 106
The European Study Group for Pancreatic Cancer ( ESPAC) Trials 110
Index 123

Produkt-Details

• Erscheint lt. Verlag: 18.1.2010
• Zusatzinfo: XI, 125 p. 4 illus., 2 illus. in color.
• Verlagsort: London
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Medizinische Fachgebiete ► Chirurgie ► Viszeralchirurgie
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Gastroenterologie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Schmerztherapie
• Themenwelt: Medizin / Pharmazie ► Pflege
• Schlagworte: Endoscopy • gastroenterology • Hematology • Oncology • pancreatic disease
• ISBN-10: 1-84882-118-2 / 1848821182
• ISBN-13: 978-1-84882-118-7 / 9781848821187