Aging Hair (eBook)

Ralph M. Trüeb, Desmond Tobin (Herausgeber)

eBook Download: PDF

2010 | 2010
XV, 270 Seiten
Springer Berlin (Verlag)
978-3-642-02636-2 (ISBN)

Infos

'Aged? But he does not appear aged, just look, his hair has remained young!' Marcel Proust, In Search of Lost Time (1913-27) The appearance of hair plays an important role in peoples' overall physical appe- ance and self-perception. With today's increasing life-expectation, the desire to look youthful plays a bigger role than ever. The hair care industry has become aware of this, and capable to deliver active products that are directed toward meeting this c- sumer demand. The discovery of pharmacological targets and the development of safe and effective drugs such as minoxidil and fnasteride also indicate strategies of the drug industry for maintenance of healthy and beautiful hair in the young and old. The study of hair aging focuses on two main streams of interest: On the one hand, the esthetic problem of aging hair and its management, in other words everything that happens outside the skin; on the other hand, the biological problem of aging hair, in terms of microscopic, biochemical, and molecular changes, in other words the 'secret life' of the hair follicle in the depth of the skin. Hair aging comprises hair shaft aging, and aging of the hair follicle. The former involves weathering and photoaging of the hair shaft, while the latter manifests as decrease of melanocyte function (graying) and decrease in hair production (alopecia).

Inhalt

Preface 5
Foreword 7
Contents 10
Gerontobiology of the Hair Follicle 15
Molecular Basis of Androgenetic Alopecia 23
Inflammatory Phenomena and Fibrosis in Androgenetic Alopecia 39
Post-Menopausal Frontal Fibrosing Alopecia 47
Female Pattern Hair Loss 54
Hair Growth Parameters in Pre- and Postmenopausal Women 62
Comparative Histopathology of Androgenetic Alopecia, Diffuse Alopecia, and Senescent Alopecia 74
Comparative Gene Expression Profiling of Senescent and Androgenetic Alopecia Using Microarray Analysis 79
The Aging Hair Pigmentary Unit 89
Oxidative Stress Associated Melanocyte- Loss and Hair Growth Capacity in the Aging Hair Follicle: A Model for Tissue- Specific Aging 102
Human Hair Follicle Melanocytes as a Proxy Cell Type in Neurodegeneration Research 112
Effect of UV Radiation on Scalp and Hair Growth 123
Hair Photoaging 132
Effect of Tobacco Smoking on Hair 143
Age-Related General Problems Affecting the Condition of Hair 148
Aging of Scalp and Age-Related Disorders of Scalp 174
Care of Aging Hair and Photoprotection 190
Possibilities and Limitations for Reversal of Age- Related Hair Loss 199
Possibilities and Limitations for Reversal of Age- Related Pigment Loss 212
Evidence-Based Hair Transplantation 219
Future Directions: Gene Polymorphism Diagnostics Relevant to Hair 225
Future Directions: The Known and Unknown Roles of Hair- Follicle Stem Cell Types 237
Future Directions: Bioengineering the Hair Follicle 243
Hair After Death 253

Produkt-Details

• Erscheint lt. Verlag: 2.4.2010
• Zusatzinfo: XV, 270 p.
• Verlagsort: Berlin
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Allgemeinmedizin
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Dermatologie
• Schlagworte: aging • androgenetic alopecia • Care • Diagnosis • Diagnostics • gene therapy • graying • hair photoaging • hair wheathering • Histopathology • prevention • senescence • senescent alopecia • Stress • therapy • Treatment • UV radiation
• ISBN-10: 3-642-02636-2 / 3642026362
• ISBN-13: 978-3-642-02636-2 / 9783642026362