Diabetic Neuropathy (eBook)

Clinical Management

Aristidis Veves, Rayaz A. Malik (Herausgeber)

eBook Download: PDF

2008 | 2nd ed. 2007
XII, 520 Seiten
Humana Press (Verlag)
978-1-59745-311-0 (ISBN)

Infos

In this updated edition, leading medical specialists critically review for the general practitioner the latest techniques for the clinical management of diabetic neuropathy. The contributors focus on the practical aspects of diabetic neuropathy and describe in detail the treatments that are currently available or expected to become available in the near future. They also include concise discussions of the pathogenesis of diabetic neuropathy.

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In this newly updated, second edition, leading medical specialists critically review for the general practitioner the latest techniques for the clinical management of diabetic neuropathy. These authoritative contributors focus on the practical aspects of diabetic neuropathy and describe in detail the treatments that are currently available or expected to become available in the near future. They also include concise discussions of the pathogenesis of diabetic neuropathy and highlight the relatively unknown features of neuropathy that can significantly impact a patient's life. Comprehensive, up-to-date bibliographies at the end of each chapter provide an opportunity for the interested physician to gain a more detailed picture of a particular topic.

Inhalt

PREFACE 7
LIST OF COLOR IMAGES 8
CONTENTS 13
CONTRIBUTORS 15
Historical Aspects of Diabetic Neuropathies 17
The Epidemiology of Diabetic Neuropathy 22
Genomics of Diabetic Neuropathy 46
Transgenic and Gene Knockout Analysis of Diabetic Neuropathy 66
Hyperglycemia-Initiated Mechanisms in Diabetic Neuropathy 83
Effectors—Sonic Hedgehog and p38 Mitogen- Activated Protein Kinase 105
Neuronal and Schwann Cell Death in Diabetic Neuropathy 126
Metabolic–Functional–Structural Correlations in Somatic Neuropathies in the Spontaneously Type 1 and Type 2 Diabetic BB- Rats 146
Experimental Diabetic Autonomic Neuropathy 166
Spinal Cord 178
Diabetic Encephalopathy 199
Microangiopathy, Diabetes, and the Peripheral Nervous System 218
Pathogenesis of Human Diabetic Neuropathy 241
Clinical Features of Diabetic Polyneuropathy 253
Micro- and Macrovascular Disease in Diabetic Neuropathy 268
Clinical Diagnosis of Diabetic Neuropathy 284
Punch Skin Biopsy in Diabetic Neuropathy 302
Aldose Reductase Inhibitors for the Treatment of Diabetic Neuropathy 317
Other Therapeutic Agents for the Treatment of Diabetic Neuropathy 329
Pathophysiology of Neuropathic Pain 346
Treatment of Painful Diabetic Neuropathy 357
Focal and Multifocal Diabetic Neuropathy 372
Hypoglycemia and the Autonomic Nervous System 384
Cardiovascular Autonomic Neuropathy 394
Postural Hypotension and Anhidrosis 418
Gastrointestinal Syndromes Due to Diabetes Mellitus 438
Genitourinary Complications 457
Management of Diabetic Foot Complications 477
Index 511

Produkt-Details

• Erscheint lt. Verlag: 1.2.2008
• Reihe/Serie: Clinical Diabetes
• Reihe/Serie: Clinical Diabetes
• Zusatzinfo: XII, 520 p.
• Verlagsort: Totowa
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Diabetologie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie
• Schlagworte: biopsy • Cell • Diabetes • Diabetes mellitus • nervous system • Pain • pathogenesis • pathophysiology • Physiology • Protein • Skin • spinal cord
• ISBN-10: 1-59745-311-0 / 1597453110
• ISBN-13: 978-1-59745-311-0 / 9781597453110