Autoimmune Diseases in Endocrinology (eBook)

Anthony P. Weetman (Herausgeber)

eBook Download: PDF

2007 | 2008
XII, 434 Seiten
Humana Press (Verlag)
978-1-59745-517-6 (ISBN)

Infos

This is a comprehensive and novel text that examines key features that predispose individuals to autoimmune diseases. The first section details the basic mechanism of autoimmunity and examines immunogenetic and environmental factors in autoimmunity. The next section examines autoimmune thyroid disease. The third section takes a look at Type 1 diabetes mellitus. In the final section, authors explain other autoimmune endocrinopathies.

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Autoimmune Diseases in Endocrinology is a comprehensive and novel text that examines key features that predispose individuals to autoimmune diseases. The text begins with three introductory chapters which provide sufficient information so that anyone, including those without a background in recent immunology, will be able to understand the developments in the field. The next and largest section of the book concerns autoimmune thyroid disease, and authors of these chapters take the reader through the basic epidemiology, genetic and environmental risk factors, immunopathogenesis, and the diagnostic and management aspect of the disease. The next section discusses Type 1 diabetes mellitus. In the final section, authors explain other autoimmune endocrinopathies, including Addison's disease, premature ovarian failure, autoimmune hypophysitis, and autoimmune polyglandular syndrome types 1 and 2. Comprehensive and timely, Autoimmune Diseases in Endocrinology will become an essential reference for all endocrinologists and internal medicine practitioners working in this field.

Inhalt

Preface 6
Contents 9
Contributors 11
PartI Introductory Chapters 13
Basic Mechanisms in Autoimmunity 14
Immunogenetic Factorsin Autoimmunity 28
Environmental Factorsin Autoimmune Endocrinopathies 46
PartII Autoimmune Thyroid Disease 87
Animal Models of Autoimmune Thyroid Disease 88
Thyroid Autoantigens 103
Graves' Disease 125
Autoimmune Hypothyroidism 144
Postpartum Thyroiditis 184
Thyroid-Associated Ophthalmopathy and Dermopathy 200
PartIII Type 1 Diabetes Mellitus 222
Animal Models of Type 1Diabetes Mellitus 223
Islet Cell Autoantigens 248
Type 1 Diabetes Mellitus 280
PartIV Other Autoimmune Endocrinopathies 306
Addison's Disease 307
Premature Ovarian Failure 334
Autoimmune Hypophysitis 359
Autoimmune Polyglandular Syndrome Type 1 395
Autoimmune Polyglandular Syndrome Type 2 413
Index 428

Produkt-Details

• Erscheint lt. Verlag: 26.12.2007
• Reihe/Serie: Contemporary Endocrinology
• Reihe/Serie: Contemporary Endocrinology
• Zusatzinfo: XII, 434 p. 28 illus.
• Verlagsort: Totowa
• Sprache: englisch
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Diabetologie
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie
• Schlagworte: autoimmune disease • Diabetes • Diabetes mellitus • endocrinology • Internal Medicine • rheumatology
• ISBN-10: 1-59745-517-2 / 1597455172
• ISBN-13: 978-1-59745-517-6 / 9781597455176