In Vivo Imaging of Cancer Therapy (eBook)

Anthony F. Shields, Pat Price (Herausgeber)

eBook Download: PDF

2007 | 2007
XII, 326 Seiten
Humana Press (Verlag)
978-1-59745-341-7 (ISBN)

Infos

A variety of cutting-edge imaging techniques, including their use for best practice, are addressed in this book. The book also provides examples of results found in both pre-clinical and clinical studies.

This comprehensive text covers the entire spectrum of in vivo imaging for oncology. It will aide clinicians at all levels in keeping up with the most cutting-edge techniques.

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Imaging studies are frequently used to evaluate the success of cancer treatments for a variety of tumor types. In Vivo Imaging of Cancer Therapy addresses a variety of cutting-edge imaging techniques, including their use for best practice, and provides examples of results found in both pre-clinical and clinical studies. This comprehensive text covers the entire spectrum of in vivo imaging for oncology, including current approaches to detailed anatomic measurements, MR and optical spectroscopy, and molecular imaging techniques requiring exogenously administered imaging agents. The challenges and approaches to quantification are also outlined. The authors describe technologies and methods that are currently clinically available, and many that are still in a developmental stage or useful only in animal studies. However, it is important to realize that the majority of imaging devices now offered for sale by the major imaging equipment manufacturers did not exist as recently as 3 or 4 years ago. Thus the pace of technology development is such that techniques described here as laboratory or investigational will likely be in clinical use within a few years. In vivo imaging will continue to have profound effects on how we think about, detect, diagnose, treat and monitor cancer. In Vivo Imaging of Cancer Therapy will aide clinicians at all levels in keeping up with the most cutting-edge techniques.

Inhalt

Foreword 6
Preface 8
Contents 10
CONTRIBUTORS 12
1 Role of Imaging in Cancer Treatment 14
2 Preclinical Models of Tumor Growth and Response 26
3 Anatomical Measure of Tumor Growth with Computed Tomography and Magnetic Resonance Imaging 46
4 Positron Emission Tomography Imaging of Blood Flow and Hypoxia in Tumors 60
5 Magnetic Resonance Measurement of Tumor Perfusion and Vascularity 85
6 Computed Tomography Measurements of Perfusion in Cancer Therapy 97
7 [18F]Fluorodeoxyglucose Positron Emission Tomography Assessment of Response 115
8 Measurement of Tumor Proliferation with Positron Emission Tomography and Treatment Response 133
9 Estrogen-Receptor Imaging and Assessing Response to Hormonal Therapy of Breast Cancer 155
10 Quantitative Approaches to Positron Emission Tomography 166
11 Positron Emission Tomography Measurement of Drug Kinetics 179
12 Imaging Genes for Viral and Adoptive Therapies 215
13 In Vivo Magnetic Resonance Spectroscopy in Clinical Oncology 250
14 Magnetic Resonance Probes for Tumor Imaging 268
15 Fluorescent Imaging of Tumors 290
16 Imaging of Apoptosis 312
Index 326

Produkt-Details

• Erscheint lt. Verlag: 6.12.2007
• Reihe/Serie: Cancer Drug Discovery and Development
• Reihe/Serie: Cancer Drug Discovery and Development
• Zusatzinfo: XII, 326 p.
• Verlagsort: Totowa
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Radiologie / Bildgebende Verfahren
• Schlagworte: Agents • Cancer Treatment • clinical research • Computed tomography (CT) • cytotoxic • Developments • Diagnosis • Drugs • Imaging techniques • magnetic resonance spectroscopy • radiation oncology • Tumor
• ISBN-10: 1-59745-341-2 / 1597453412
• ISBN-13: 978-1-59745-341-7 / 9781597453417