Mechanistic Enzymology and Drug Design
Royal Society of Chemistry (Verlag)
978-1-84973-015-0 (ISBN)
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1. Discusses enzyme targets that have been used to develop drugs
2. There are many new drugs being developed that particularly target specific enzymes.
3. Biochemists, medicinal chemists, academia and industry
4. Biomolecular science series, MedChemComm
5. The book will survey enzyme targets that have successfully been used to develop clinically-utilized drugs and to describe in detail how these drugs inhibit these particular enzymes.
Professor John F Honek is currently Professor and Chair at the Department of Chemistry, University of Waterloo, Waterloo, Canada. He gained his BSc and PhD in Chemistry at McGill University, Montreal, Canada and was a Postdoctoral Fellow at the Department of Chemistry, MIT, Boston, USA. As a graduate student at McGill, he was involved in the medicinal chemistry of anticancer agents and at MIT, he was involved in mechanistic enzymology. He currently heads a laboratory of 14 students and research associates involved in mechanistic enzymolgy of metalloenzymes and is also involved in the design and synthesis of mechanism-based enzyme inhibitors. He is on the editorial board of 5 journals and has been on Canadian NSERC research grant agency committees. He also has peer reviewed research grants for Canadian, USA and Asian research granting agencies in the areas of biological chemistry and drug design and for several years he was on the Scientific Advisory Board of a California biotechnology company focused on drug design.
Mechanistic Enzymology and Drug Design; EC Enzyme Class 1: Oxidoreductases; EC Enzyme Class 2: Transferases; EC Enzyme Class 3: Hydrolases; EC Enzyme Class 4: Lyases; EC Enzyme Class 5: Isomerases; EC Enzyme Class 6: Ligases; Where do we go from here?
| Erscheint lt. Verlag | 5.6.2018 |
|---|---|
| Reihe/Serie | Drug Discovery |
| Zusatzinfo | No |
| Verlagsort | Cambridge |
| Sprache | englisch |
| Maße | 156 x 234 mm |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
| Naturwissenschaften ► Biologie ► Biochemie | |
| Naturwissenschaften ► Chemie ► Organische Chemie | |
| Technik ► Umwelttechnik / Biotechnologie | |
| ISBN-10 | 1-84973-015-6 / 1849730156 |
| ISBN-13 | 978-1-84973-015-0 / 9781849730150 |
| Zustand | Neuware |
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