Endothelin in Renal Physiology and Disease

Buch | Hardcover

266 Seiten

2011
Karger, S (Verlag)
978-3-8055-9794-4 (ISBN)

Titel leider nicht mehr lieferbar

Artikel merken

Endothelin is a 21-amino acid peptide that exerts uniquely potent and long-lasting effects on the kidney, including regulation of water and electrolyte excretion, blood pressure, cell growth, inflammation and fibrosis. During the past 10 years, the field has evolved rapidly; we are now uncovering the potential importance of endothelin receptor antagonists (ERAs) in the treatment of kidney disease. This book reviews experimental concepts, preclinical studies and clinical data which form the basis of our current understanding of the association between endothelin and kidney disease. Acclaimed experts in pharmacology, molecular biology, physiology, cardiovascular medicine, and nephrology have contributed timely reviews dealing with renal pharmacology and physiology of endothelin, the role of endothelin in renal disease development and ERAs in preclinical studies, and the current state of clinical development of ERA therapy in renal medicine. The publication at hand will be a valuable reference source for nephrologists, internists and other healthcare professionals, renal physiologists and molecular biologists, post-doctoral researchers and students in the life sciences, as well as for scientists and decision makers in drug research and development.

Erscheint lt. Verlag	12.9.2011
Reihe/Serie	Contributions to Nephrology ; 172
Mitarbeit	Herausgeber (Serie): Ronco
Zusatzinfo	35 fig., 9 in color, 3 tab.
Verlagsort	Basel
Sprache	englisch
Gewicht	717 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Nephrologie
Schlagworte	biochemistry • Cardiovascular System • Diabetes • Molecular Biology • Nephrologie • Nephrology • pharmacology • Physiology
ISBN-10	3-8055-9794-0 / 3805597940
ISBN-13	978-3-8055-9794-4 / 9783805597944
Zustand	Neuware