Cancer Epigenetics – Biomolecular Therapeutics in Human Cancer
John Wiley & Sons Inc (Hersteller)
978-1-118-00574-3 (ISBN)
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Antonio Giordano , M.D., Ph. D., is professor of biology and medical research at Temple University College of Science and Technology in Philadelphia, Pennsylvania. In 1993 he co-founded the Sbarro Institute for Cancer Research and Molecular Medicine. He has been honored as Knight by the president of Italy and is recipient of the National Italian-American Political Action Committee (NIA-PAC) National Lifetime Achievement Award in Medical Research. Marcella Macaluso , Ph.D., is associate professor of biology and a researcher in the Hormone-Signaling and Cancer Program of the Sbarro Institute for Cancer Research at Temple University in Philadelphia.
Contributors. Preface. SECTION I: EPIGENETICS AND CELL CYCLE. 1 Epigenetic Modulation of Cell Cycle: An Overview ( Micaela Montanari, Antonio Giordano, Marcella Cintorino, and Marcella Macaluso ). SECTION II: EPIGENETICS AND CELL DEVELOPMENT, SENESCENCE AND DIFFERENTIATION. 2 Epigenetics in Skeletal Muscle Development ( Cristina Giacinti and Antonio Giordano ). 3 Epigenetic Control in Cellular Senescence ( Heike Helmbold, Wolfgang Deppert, and Wolfgang Bohn ). 4 Epigenetic Modulation in Cell Development and Differentiation ( Mario Mancino, Claudia Esposito, Raffaella Pasquale, Immacolata Vocca, and Francesca Pentimalli ). SECTION III: EPIGENETICS AND GENE TRANSCRIPTION. 5 Epigenetic Control of Gene Transcription ( Christian Bronner, Mayada Achour, Thierry Chataigneau,and Valerie B. Schini-Kerth ). 6 Epigenetics, MicroRNAs, and Cancer: An Update ( Giuseppe Russo, Andrew Puca, Francesco Masulli, Stefano Rovetta,Letizia Cito, Debora Muresu, Flavio Rizzolio, and Antonio Giordano ). SECTION IV: EPIGENETICS AND CANCER. 7 The Role of Epigenetic Modifications in Cancer ( Michael J. Powell, Vladimir M. Popov, Xiang Wang, Steven B. McMahon,Alexander Mazo, and Richard G. Pestell ). 8 MBD4/MED1 Protein in DNA Repair and Demethylation, Cancer, and Other Diseases ( Serena Buontempo, Mara Sannai, and Alfonso Bellacosa ). 9 Epigenetics in Pediatric Cancers ( Roberta Ciarapica, Lavinia Raimondi, Federica Verginelli, and Rossella Rota ). 10 Epigenetic Mechanisms in Cancer Formation and Progression ( Elisabetta Fratta, Luca Sigalotti, Alessia Covre, Giulia Parisi, Riccardo Danielli, Hugues Jean Marie Nicolay, Sandra Coral, and Michele Maio ). SECTION V: EPIGENETICS AND ANTICANCER DRUG DEVELOPMENT AND THERAPY. 11 Recent Advances in the Field of Stem Cell Research: Toward the Definition of the Epigenetic and Genetic Codes of Pluripotency ( Gaetano Romano ). 12 Potential of Heat Shock Protein Targeting for Human Therapy ( Laszlo Otvos, Jr ). 13 Advances in Stem Cell Therapy for Cancer Research ( Andrew Puca and Antonio Giordano ). 14 Epigenetic Targets and Drug Development ( Paraskevi Vogiatzi, Maria Irene Scarano, and Pier Paolo Claudio ). Index.
Erscheint lt. Verlag | 7.6.2011 |
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Verlagsort | New York |
Sprache | englisch |
Maße | 150 x 250 mm |
Gewicht | 666 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
ISBN-10 | 1-118-00574-0 / 1118005740 |
ISBN-13 | 978-1-118-00574-3 / 9781118005743 |
Zustand | Neuware |
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