New Trends in Hepatology

The Proceedings of the Annual Meeting of the Italian National Programme on Liver Cirrhosis and Viral Hepatitis, San Miniato (Pisa), Italy, 7–9 January, 1996

P. Gentilini, M.U. Dianzani (Herausgeber)

Buch | Hardcover

352 Seiten

1996 | 1996 ed.
Springer (Verlag)
978-0-7923-8703-9 (ISBN)

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The Italian Group for the Study of Liver Cirrhosis began its activity in 1980 on the basis of recognition and financial support from the Italian Ministry of the University, Scientific Research and Technology, having been chosen from several other scientific programs. The group is now called the National Group for the Study of Liver Cirrhosis and Viral Hepatitis and includes more than 40 centers throughout the nation under the auspices of the universities. The primary Imtlatlve of the group, to combine experimental and clinical approaches in the study of liver pathophysiology, remains unchanged. Annual meetings in January provide the possibility of comparing experimental and clinical results in the spirit of mutual comprehension and criticism. After 15 years and 6 volumes (published biannually), the actual improvement of Italian research in liver pathophysiology is evident. In fact, in order to let other researchers know what has been achieved we chose to publish the 7th volume, in spite of the economic difficulties at hand. We have gathered specific experiences of all the centers included in the national program. Each group was required to present an update in its own field of research, rather than specific or recently obtained results, which could have been reported only in relationship with other data already published by others. Like the 6th edition in our series, this volume affirms the specific competence of all the participants and summarizes the most important updates in liver pathophysiology.

Foreword. Section 1: Pathogenetic Mechanisms of Liver Injury. 1. 4-Hydroxy Alkenals, Products of Lipid Peroxidation, as Signals for Biochemical Functions of Normal Cells; M.U. Dianzani. 2. Oxidative Stress and Protein Kinase C Activity Modulation; C. Domenicotti, et al. 3. Oxidative Damage in Chronic Liver Disease; E. Baldi, et al. 4. Chronic Ethanol Consumption Impairs Dolichol Levels and Glycosylation Processes in Rat Liver Microsomes and Golgi Apparatus; D. Cottalasso, et al. 5. Compartmentation and Redox State of Thiols and Proteins During Acute Ethanol Intoxication in Rats; E. Altomare, et al. 6. Possible Role of Ethanol-Derived Free Radicals in the Pathogenesis of Alcohol-Induced Liver Damage; E. Albano, et al. 7. Hepatic Iron Overload Induced by Phenylhydrazine: Release of Iron in a Free Form and DNA Damage; M. Comporti, et al. 8. The Effects of Development of the MDR 1 Phenotype on Cell Susceptibility to Undergoing Lipid Peroxidation and Ionizing Radiation; R. Mazzanti, et al. 9. Molecular and Cellular Aspects of Iron-Mediated Liver Toxicity; A. Pietrangelo, et al. 10. The Cellular and Molecular Basis of Liver Fibrogenesis; M. Pinzani, et al. 11. Proliferation of Hepatic Stellate Cells and Lipid Peroxidation: Changes Due to Polyphenols; G. Svegliati Baroni, et al. 12. Reoxygenation Injury in Isolated Rat Hepatocytes; P. Caraceni, et al. 13. Oxidative Stress and Cell Damage Following Orthotopic Liver Transplantation; E. Chiarpotto, et al. 14. The Genomic Response of Liver Cells to Post-Ischemic Reperfusion and Oxidative Stress; A. Bernelli-Zazzera. Section 2: Pathophysiology of Bile Secretion. 15. Cytotoxic and Protective Effects of Bile Salts in Vitro; F. Carubbi, et al. 16. Lamellar Bodies in Human Gallbladder Bile; S. Ginanni Corradini, et al. 17. Hepatocyte Lipid-Metabolic Interplays and the Cholesterol Secretion Process to Bile: Insights from Rat Studies; M. Carrella. Section 3: Insights in Hepatic Carcinogenesis. 18. Lipid Peroxidation and Hepatocarcinogenesis: &ggr;-Glutamyl Transpeptidase-Dependent Oxidant Stress in Hepatic Preneoplastic Lesions and HEPG2 Hepatoma Cells; A. Pompella, et al. 19. Antioxidant System in Hepatocellular Carcinoma; A. Grattagliano, et al. 20. Loss of Heterozygosity of the Long Arm of Chromosome 16 in Hepatocellular Carcinoma on Liver Cirrhosis; L. Gramantierei, et al. 21. Potential Molecular Mechanisms of Viral Liver Carcinogenesis; M.S. De Mitri, et al. 22. Prevalence of Wild-Type and Variant Transcripts of Liver Estrogen Receptors in Chronic Liver Disease; E. Villa, et al. Section 4: Pathogenetic Aspects of Hepatitis C Virus (HCV) Infection. 23. Molecular Biology of HCV: Implications in Epidemiology and Diagnosis of Infection; M. Rapicetta, et al. 24. Cell-Mediated Immune Response in Hepatitis C Virus (HCV) Infection: Are Different Strategies Adopted by HCV and Hepatitis B Virus to Persist?; F. Fiaccadori, et al. 25. The Epidemiological and Clinical Aspects of Hepatitis C in Italy; F. Morisco, et al. 26. Diagnostic Evaluation of Patients with Chronic HCV Infection; S. Nardiello, et al. 27. Correlation Between Hepatitis C Virus RNA Levels i

Zusatzinfo	352 p.
Verlagsort	Dordrecht
Sprache	englisch
Gewicht	714 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Hepatologie
ISBN-10	0-7923-8703-1 / 0792387031
ISBN-13	978-0-7923-8703-9 / 9780792387039
Zustand	Neuware