Nephrology

Buch | Hardcover

1976 Seiten

1984 | 1984 ed.
Springer-Verlag New York Inc.
978-0-387-96072-2 (ISBN)

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For many reasons, as President of the International Society of Nephrology, I am happy and honored to write a brief introduction to Nephrology, the Proceedings of the IXth International Congress of Nephrology. One of these reasons is specially treasured: I edited the two books published after our first Congress (Geneva-Evian 1960). The 1984 vintage will certainly be as good as the preceding ones. And, for any nephrologist, whatever his or her field of interest, many observations will be found in the Proceedings that will enhance their personal work. It is characteristic for our Congresses to be the converging point upon which many different orientations join together and form the nephrology that is researched and practiced throughout the world. What could replace a State-of-the-Art lecture delivered by a selected ne phrologist whose work is of the highest quality? At times, even more revealing are those presentations made by non-nephrologists, the basic scientists who bring us fresh data and new concepts far removed from the reader's daily world. But attending such a lecture is never enough. Their texts should be read and reread. Symposia and workshops, as sources of precise and up dated knowledge espoused by experts, are often heart-breaking as they shake established dogma. Therefore, they should be neither neglected nor forgotten but scrutinized carefully. The evidence which could eventually lead to new concepts or hypotheses has to be weighed accurately and then either rejected, discarded temporarily, or accepted, even if the latter implies dramatic change."

I.- Volume I.- Normal Structure and Function.- Transport Processes and Epithelia.- Determinants of Growth, Form, and Function in Epithelia.- Basolateral Membrane Properties of Sodium-absorbing Epithelia.- Sodium-Glucose Cotransport Mechanisms.- Cell Volume Regulation in Epithelia.- Role of Cytosolic Calcium in Vasopressin-sensitive Epithelia.- Role of Cytosolic Calcium in Renal Tubular Transport.- Sodium Phosphate Cotransport: Studies with Vesicles and LLC-PK1 Cells.- Regulation of the Na+/H+ Antiporter in Cells of the Proximal Tubule.- Renal Nerves.- Functions of the Renal Nerves.- Renal Circulation.- Organization of the Medullary Circulation: Functional Implications.- Pathophysiology of the Medullary Circulation.- Intrarenal Control of Medullary Blood Flow and the Urinary Concentrating Mechanism.- Glomerular Filtration.- Intrarenal Control of Glomerular Filtration: Cellular Mechanisms of Tubuloglomerular Feedback.- Regulatory Role of the Tubuloglomerular Feedback Mechanism.- Influence of Renal Nerves on the Glomerular Microcirculation.- Structure and Transport Along the Nephron.- Hydrogen Ion Transport Along the Nephron.- Proximal Tubule Transport.- Transport Properties of the Pars Recta.- Function of the Thin Limb of Henle’s Loop.- Regulation of Sodium Chloride Transport by the Loop of Henle.- Sodium Chloride Reabsorption in the Thick Ascending Limb of the Loop of Henle.- Structural Heterogeneity of the Distal Nephron.- Control of Acid and Electrolyte Excretion.- Acidification Mechanisms.- Atrial Natriuretic Factor.- Regulation of Potassium Excretion.- Renal Metabolism, Prostaglandins, and Renin.- Contemporary Issues in Renal Metabolism.- Biochemistry of Renal Prostaglandins.- From Molecular Biology to Antihypertensive Drugs: Current Research on Renin Inhibitors.- Inactive Renin.- The Renin Gene: Structure and Processing of Renin.- Intracellular Actions of Renin.- The Endocrine System and the Kidney.- Similarity of the Effects of Antidiuretic Hormone, Parathyroid Hormone, Calcitonin, and Glucagon on Rat Kidney.- Brush Border and Basal-Lateral Membranes in the Action of Thyroid Hormone on the Proximal Tubule.- Binding of Aldosterone and Corticosterone Along the Nephron and Effects on Na-K-ATPase.- Localization of Aldosterone Receptors Along the Nephron.- Mechanism of Action of Aldosterone: Effects on Sodium, Potassium, and Hydrogen Transport.- Mechanism of Action of Aldosterone: Role of Na-K-ATPase.- Renal Actions by Which Vasopressin May Aid the Concentration of Urine.- Cellular Modes of Action of Vasopressin.- Specificity of Agonistic and Antagonistic Analogues of Vasopressin.- Cardiovascular Effects of Vasopressin.- Alterations of Extracellular Fluid Volume.- Edema.- Newer Concepts of Starling Equilibrium at the Capillary Level in the Production of Edema.- Pathogenesis of Edema in Cirrhosis.- Renal Handling of Sodium in Hepatic Diseases Other than Cirrhosis.- Primary Renal Sodium Retention in the Nephrotic Syndrome.- Causes and Mechanisms of Renal Injury.- Immunologic Mechanisms in Renal Disease.- Cellular and Humoral Mediators of Renal Injury.- Mechanisms of Immune Complex Formation and Deposition in Glomeruli.- Characteristics of Circulating Immune Complexes That Deposit in Renal Glomeruli.- Etiologic Factors in Immunologically Mediated Glomerulonephritis.- Role of Antigen and Antibody Charge in Immune Complex Disease.- Pathogenic Antigen of Heymann Nephritis (gp330): Identification, Isolation, and Localization.- Monoclonal Antibodies as Probes of Normal and Abnormal Renal Structure.- Role of Proteoglycans in Glomerular Function and Pathology.- Glomerular Arachidonic Acid Metabolism in Nephrotoxic Serum Nephritis.- Effects of Dexamethasone on Cultured Mesangial Cell Function During Phagocytosis.- Diseases of the Kidneys.- Primary Glomerular Diseases.- Poststreptococcal Glomerulonephritis.- Minimal Change Disease, Mesangial Proliferative Glomerulonephritis and Focal Sclerosis: Individual Entities or a Spectrum of Disease?.- Pathogenetic Mechanisms of IgA Nephropathy from Studies of Experimental Models.- Immunologic Aspects of IgA Nephropathy in Humans.- Clinicopathologic Correlations in IgA Nephropathy.- Natural History and Treatment of Idiopathic IgA Nephropathy.- Acute Renal Failure.- Principles of Acute Renal Failure.- Pathology of Acute Renal Failure.- Experimental Acute Renal Failure: Pathophysiology and Methods of Protection.- Control of Renal Regeneration After Acute Tubular Necrosis.- Contribution of Proteases to Hypercatabolism in Acute Renal Failure.- Cellular Mechanisms of Protection in Nephrotoxic and Ischemic Acute Renal Failure.- Clonidine, Propranolol, and the Prevention of Acute Renal Failure.- The Role of Calcium Channel Blockers.- Adenine Nucleotides in the Prevention of Ischemic Acute Renal Failure.- Nephrotoxicity.- Mechanisms of Drug Nephrotoxicity.- Nephrotoxicity of Nonsteroidal Anti-Inflammatory Drugs.- Renal Damage Induced by Radiologic Contrast Media.- Antibiotic-Induced Nephrotoxicity.- Nephrotoxicity Caused by Cancer Chemotherapy.- Volume II.- The Kidney in Systemic Disease.- Renal Involvement in Multiple Myeloma.- Pathology of Light Chain Nephropathies.- Glomerular Lesions in Lymphomas and Leukemias.- Sickle Cell Nephropathy.- Tubular Defects.- Isolated Tubular Defects.- Obstructive Uropathy and Urinary Reflux.- Pathophysiology of Obstructive Uropathy.- Vesicoureteral Reflux and Renal Damage.- Renal Scars and Vesicoureteric Reflux: Pathology and Pathogenesis of Segmental Atrophy.- Natural History and Treatment of Reflux Nephropathy.- Urolithiasis.- Pathogenesis of Calcium Renal Stones.- Physicochemical Factors in Calcium Oxalate Urolithiasis.- Use of Thiazide Diuretics in Calcium Oxalate Nephrolithiasis.- Agents Other Than Thiazide Diuretics in the Treatment of Calcium Oxalate Nephrolithiasis.- Urinary Inhibitors of Calcium Oxalate Crystallization.- Kidney Diseases in the Tropics.- Nephrotic Syndrome in Tropical Africa: Glomerulonephritis in Zimbabwe.- Renal Involvement in Leptospirosis.- Diabetes Mellitus and the Kidney.- Clinical and Renal Functional Studies of Diabetic Nephropathy in Humans.- Altered Glomerular Metabolism in Diabetes Mellitus.- Pathophysiology of Proteinuria in Diabetic Nephropathy.- Early Markers of Diabetic Nephropathy: A Road to Prevention.- Can the Insulin-Dependent Diabetic Patient Be Managed Without Kidney Biopsy?.- Pathogenesis as a Determinant of Therapy in Diabetic Nephropathy.- Hypertension.- Hypertension: Current Concepts of Mechanism and Management.- Effect of Dietary Fish Oils on Eicosanoid Formation in Platelets, Neutrophils, and the Cardiovascular-Renal System.- Calcium, Phosphate, and Parathyroid Hormone in Blood Pressure Regulation.- Role of Sodium and Other Dietary Factors in Hypertension.- Hypertension in the Elderly.- Mechanisms of Action and Use of Newer Antihypertensive Agents.- An Analysis for and Against Treatment of Mild Hypertension.- Phosphate Depletion.- Clinical Spectrum of Phosphate Depletion and Its Effects on Urinary Acidification.- Effect of Phosphate Depletion on Renal Tubular Transport.- Phosphate Depletion and Renal Cell Metabolism.- Mechanisms of Myocardial Injury in Phosphate Depletion.- Pathogenesis and Consequences of Chronic Renal Failure.- Mechanisms of Progression of Renal Disease.- Pathogenesis of Uremia.- Endocrine and Metabolic Abnormalities.- Regulation of Parathyroid Gland Activity.- The Status of Parathyroid Hormone Measurements in Humans.- Parathyroid Hormone: Alterations in Chronic Renal Failure.- Vitamin D and Kidney Disease.- Endocrine and Metabolic Abnormalities in Acute Renal Failure.- Insulin, Glucose, Amino Acid, and Lipid Metabolism in Chronic Renal Insufficiency.- Endocrine and Metabolic Abnormalities in the Nephrotic Syndrome: Calcium and Carbohydrate Metabolism.- Osteodystrophy.- Renal Osteodystrophy: General Concepts and Current Issues.- Prevalence of Various Types of Bone Disease in Dialysis Patients.- Role of Aluminum Accumulation in Renal Osteodystrophy.- Treatment of Renal Osteodystrophy in Chronic Renal Failure.- Hematopoietic System.- Prostanoid-Related Platelet Abnormalities in Renal Disease.- Gastrointestinal.- Intestinal Transport of Minerals in Renal Failure.- Evaluation and Management of Kidney Diseases and Renal Failure.- Microscopic and Biochemical Analysis of the Urine in the Evaluation of Kidney Disease.- Newer Imaging Techniques in Nephrology.- Are Randomized Trials in Kidney Disease Worthwhile?.- Infections.- Current Concepts in the Management of Urinary Tract Infections.- Treatment of Glomerular Diseases.- Treatment of Glomerulonephritis Based on Knowledge of Its Pathogenesis.- Use of Pulse Methylprednisolone in Primary and Multisystem Glomerular Diseases.- Plasma Exchange for Glomerular Disease.- Treatment of Glomerular Disease with Anticoagulant, Antiplatelet, and Nonsteroidal Anti-inflammatory Agents.- Nutrition in Renal Failure.- Causes of Catabolism and Wasting in Acute or Chronic Renal Failure.- Influence of Nutritional Therapy on Progression of Renal Insufficiency.- Dialysis.- Advantages and Disadvantages of Current Dialysis Techniques.- Vascular Access for Hemodialysis.- Anatomic and Physiologic Aspects of Peritoneal Dialysis.- Efficacy and Adequacy of Continuous Ambulatory Peritoneal Dialysis.- Continuous Ambulatory Peritoneal Dialysis in Diabetic Patients.- Long-Term Metabolic Consequences of Continuous Ambulatory Peritoneal Dialysis.- Transplantation.- Renal Transplantation: Current Status.- Endocrine and Metabolic Dysfunctions Following Kidney Transplantation.- Cyclosporine in Renal Transplantation.- The Transfusion Effect in Renal Allograft Recipients.- Antilymphocyte Globulin and Monoclonal Antibodies: Present Status as Therapy.- Total Lymphoid Irradiation in Renal Transplantation: Reduction and Elimination of Maintenance Immunosuppressive Drugs.- Adjuvant Methods of Immunomodulation for Transplantation.- Immunological Monitoring and Renal Transplantation.

Mitarbeit	Sonstige Mitarbeit: V W Dennis, T F Ferris, R J Glassock, J P Kokko
Verlagsort	New York, NY
Sprache	englisch
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Nephrologie
ISBN-10	0-387-96072-4 / 0387960724
ISBN-13	978-0-387-96072-2 / 9780387960722
Zustand	Neuware