Frontiers in Diabetes / The Insulinotropic Gut Hormone Glucagon-Like Peptide-1

H C Fehmann, B Göke, M Porta, F M Matschinsky (Herausgeber)

Buch | Hardcover

VIII, 240 Seiten

1997
Karger, S (Verlag)
978-3-8055-6165-5 (ISBN)

Infos

Frontiers in Diabetes; Bd 13

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Glucagon-like peptide-1 (GLP-1) is a promising new therapeutic tool for the treatment of diabetes. Since the first reports describing its potent insulinotropic activity were published about a decade ago, knowledge of the incretin hormones, and GLP-1 in particular, has increased significantly. This timely volume summarizes what is now known about the molecular biology, physiology and pharmacology of GLP-1. Thorough coverage is given to the physiology of the hormone, including its generation, release and actions at pancreatic and extrapancreatic tissues. The intracellular mechanisms of GLP-1 are also described in detail. Discussion of the molecular biology includes the structure and functions of the genes coding for proglucagon and the GLP-1 receptor. A special feature of the book is the clinical information provided which includes data on the expression and release of GLP-1 and its potential use as a therapeutic agent for diabetes. Presenting the results of exciting new research, this book will be a valuable reference for endocrinologists, gastroenterologists, pharmacologists, physiologists and biochemists interested in this important hormone.

Produkt-Details

• Reihe/Serie: Frontiers in Diabetes ; BD 13 | 1.130
• Zusatzinfo: 63 figs., 20 tab.
• Sprache: englisch
• Maße: 170 x 240 mm
• Gewicht: 646 g
• Einbandart: gebunden
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie
• Schlagworte: Diabetes • Diabetes mellitus • Diabetes mellitus / Zuckerkrankheit • endocrinology • gastroenterology • Glucagon • HC/Medizin/Klinische Fächer • Peptide
• ISBN-10: 3-8055-6165-2 / 3805561652
• ISBN-13: 978-3-8055-6165-5 / 9783805561655
• Zustand: Neuware