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Cellular Drug Delivery -

Cellular Drug Delivery

Principles and Practice

D. Robert Lu, Svein Øie (Herausgeber)

Buch | Softcover
376 Seiten
2010 | Softcover reprint of hardcover 1st ed. 2004
Humana Press Inc. (Verlag)
978-1-61737-455-5 (ISBN)
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An authoritative and up-to-date survey of the fundamental principles, and practice of drug delivery at the cellular level. On the principles side, the authors discuss the broad spectrum of cellular delivery, ranging from coverage of cell-mediated immunity, gene delivery, and protein targeting, to cellular drug transport, cellular drug permeability, and a variety of carrier system related to targeted drug delivery. On the practice side, the authors focus on technological developments in cellular drug delivery, including novel formulations for the delivery of DNA and antisense oligonucleotides ,as well as drug targeting with immunoglobulin formulations and antibody-mediated approaches.

to Cellular Drug Delivery: Present Realities and Future Prospects.- I. Fundamentals of Cell Biology and Cellular Drug Delivery.- 1. Cellular Structure, Function, and Membrane Transport.- 2. Cellular Growth, Development, and Defensive Response.- II. Principles of Cellular Drug Delivery.- 3. Augmentation of Cell-Mediated Immunity to Virus.- 4. Development of Nonviral DNA Delivery Systems.- 5. Nucleic Acid Cellular Delivery.- 6. TAT and TAT-Like Peptides for Protein Transduction and Intracellular Drug Delivery.- 7. Carrier-Mediated Mechanisms for Cellular Drug Transport.- 8. ABC Transporter Proteins and Cellular Drug Resistance: P-Glycoprotein and Analogous Transporters.- 9 Human Intestinal Cellular Characteristics and Drug Permeability.- 10. Targeted Drug Delivery to Tumor Cells Using Colloidal Carriers.- 11. Biological Protein Nanostructures and Targeted Drug Delivery.- III. Practice and Technology of Cellular Drug Delivery.- 12. Formulation Considerations for DNA-Based Therapeutics.- 13. Cationic Microparticles and Emulsions As Effective Delivery Systems for Immune Stimulatory CpG DNA.- 14. Transdermal Delivery of Antisense Oligonucleotides.- 15. Fc Receptor Targeting With Recombinant Immunoglobulins and Immunoglobulin Formulations.- 16. Antibody-Mediated Drug Delivery in Cancer Therapy.- 17. Automated Property Profiling for Cellular Drug Delivery.

Erscheint lt. Verlag 5.11.2010
Zusatzinfo 50 Illustrations, black and white; X, 376 p. 50 illus.
Verlagsort Totowa, NJ
Sprache englisch
Maße 178 x 254 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Pflege
Medizin / Pharmazie Pharmazie PTA / PKA
ISBN-10 1-61737-455-5 / 1617374555
ISBN-13 978-1-61737-455-5 / 9781617374555
Zustand Neuware
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