Therapeutic Hypothermia

Samuel Tisherman, Fritz H. Sterz (Herausgeber)

Buch | Softcover

258 Seiten

2010 | Softcover reprint of hardcover 1st ed. 2005
Springer-Verlag New York Inc.
978-1-4419-3793-3 (ISBN)

Artikel merken

Samuel A. Tisherman, MD', Fritz Sterz, MD~ '~niversit~ of Pittsburgh, Pittsburgh, PA, USA 2~edical University of Vienna, Vienna, Austria The use of hypothermia for a variety of therapeutic purposes has a long and erratic history. Hippocrates recommended the use of topical cooling to stop bleeding. Fay used cooling of the extremities for patients with tumors in the 1930s. It wasn't until the 1950s, when the effects of hypothermia on systemic oxygen metabolism became better defined, that systemic hypothermia became a commonly used modality, particularly for cardiac surgery. Hypothermia was used for protection (treatment before the insult) and preservation (treatment during the insult) of the heart and entire organism during planned operative ischemia. Shortly thereafter, attempts were made to use hypothermia for resuscitation (treatment after the insult) from cardiac arrest and for management of head trauma. At that time, it was felt that moderate hypothermia (28-32OC) was needed. This was difficult to achieve and manage. Multiple complications were noted. Consequently, therapeutic, resuscitative hypothermia lay dormant for many years while mild (32-35°C) to moderate hypothermia became common for many cardiothoracic and neurosurgical procedures. In the early 1990s, it was found that mild hypothermia, even after cardiac arrest, had benefit for the brain. Similar results were found with head trauma. This lead to a burst of enthusiasm for research into resuscitative hypothermia for a variety of insults, most of which have tissue ischemia as a major component.

Global Brain Ischemia: Animal Studies.- Global Cerebral Ischemia: Clinical Studies.- Focal Cerebral Ischemia: Mechanisms.- Focal Cerebral Ischemia: Clinical Studies.- Traumatic Brain Injury: Laboratory Studies.- Traumatic Brain Injury: Clinical Studies.- Spinal Cord Ischemia and Trauma.- Asphyxia.- Neonatal Asphyxia.- Hemorrhagic Shock and Exsanguination Cardiac Arrest.- Adult Respiratory Distress Syndrome and Sepsis.- Liver Failure and Intracerebral Hypertension.- Myocardial Ischemia and Infarction.- Cooling Methods.- Detrimental Effects of Hypothermia.- Future Directions.

Erscheint lt. Verlag	23.11.2010
Reihe/Serie	Molecular & Cellular Biology of Critical Care Medicine ; 4
Zusatzinfo	XIV, 258 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Intensivmedizin
Themenwelt	Studium ► Querschnittsbereiche ► Klinische Umweltmedizin
ISBN-10	1-4419-3793-5 / 1441937935
ISBN-13	978-1-4419-3793-3 / 9781441937933
Zustand	Neuware