Biochemistry of Antimicrobial Action

Trevor John Franklin, G. A. Snow (Autoren)

Buch | Softcover

224 Seiten

1975 | 2nd ed. 1975
Chapman and Hall (Verlag)
978-0-412-12910-0 (ISBN)

Artikel merken

The rapid advances made in the study of the synthesis, structure and function of biological macromolecules in the last fifteen years have enabled scientists concerned with antimicrobial agents to achieve a considerable measure of understanding of how these substances inhibit cell growth and division. The use of antimicrobial agents as highly specific inhibitors has in turn substantially assisted the investigation of complex biochemical processes. The literature in this field is so extensive however, that we considered an attempt should be made to draw together in an introductory book the more significant studies of recent years. This book, which is in fact based on lecture courses given by us to undergraduates at Liverpool and Manchester Universities, is therefore intended as an introduction to the biochemistry of antimicrobial action for advanced students in many disciplines. We hope that it may also be useful to established scientists who are new to this area of research. The book is concerned with a discussion of medically important antimicrobial compounds and also a number of agents that, although having no medical uses, have proved invaluable as research tools in biochemistry. Our aim has been to present the available information in a simple and readable way, emphasizing the established facts rather than more controversial material. Whenever possible, however, we have indicated the gaps in the present knowledge of the subject where further information is required.

The development of antimicrobial agents, past, present and future.- The bacterial cell wall — a vulnerable shield.- Antiseptics, antibiotics and the cell membrane.- Suppression of gene function 1.- Suppression of gene function 2.- Synthetic antimicrobial agents and compounds with special applications.- Penetrating the defences: How antimicrobial agents reach their targets.- The problems of resistance to antimicrobial drugs.

Zusatzinfo	7 Illustrations, black and white; XII, 224 p. 7 illus.
Verlagsort	London
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
Themenwelt	Medizin / Pharmazie ► Pharmazie
ISBN-10	0-412-12910-8 / 0412129108
ISBN-13	978-0-412-12910-0 / 9780412129100
Zustand	Neuware