Cooley's Anemia
Wiley-Blackwell (Verlag)
978-1-57331-782-5 (ISBN)
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Thanks to scientific advances, individuals with thalassemia—a group of genetic blood disorders which includes Cooley's Anemia — are now living into their 40's and 50's. Not only are individuals living longer, but their quality of life has increased. Scientific and clinical advancements have resulted in new iron-chelating drugs, early detection of organ failure, an understanding of adult complications associated with living with thalassemia (osteoporosis, heart failure, growth hormone deficiency, pulmonary hypertension, and infertility) and promising progress towards the ultimate magic bullet—a cure in the form of bone marrow and cord blood transplants, or gene therapy.
This volume integrates basic science and clinical research so that both scientists and clinicians can develop a mutual understanding of recent progress in thalassemia.
NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.
Elliott P. Vichinsky is the editor of Cooley's Anemia: Ninth Symposium, Volume 1202, published by Wiley. Ellis Neufeld is the editor of Cooley's Anemia: Ninth Symposium, Volume 1202, published by Wiley.
Clinical trials in thalassemia: insights from the patient community Pathogenesis and management of iron toxicity in thalassemia
The role of antioxidants and iron chelators in the treatment of oxidative stress in thalassemia
Thalassemia as a global health problem: recent progress toward its control in the developing countries
Iron metabolism and ineffective erythropoiesis in [beta]-thalassemia mouse models
Hepcidin in [beta]-thalassemia
Therapy for [beta]-globinopathies: a brief review and determinants for successful and safe correction
Humanized mouse models of Cooley's anemia: correct fetal-to-adult hemoglobin switching, disease onset, and disease pathology
Strategy for a multicenter phase I clinical trial to evaluate globin gene transfer in [beta]-thalassemia
Hematopoietic stem cell mobilization strategies for gene therapy of beta thalassemia and sickle cell disease
Transcriptional silencing of fetal hemoglobin by BCL11A
The challenge of obtaining therapeutic levels of genetically modified hematopoietic stem cells in [beta]-thalassemia patients
Deferiprone
Combined iron chelation therapy
Deferasirox: current knowledge and future challenges
Monitoring the efficiency of iron chelation therapy: the potential of nontransferrin-bound iron
Critical appraisal of growth retardation and pubertal disturbances in thalassemia
Magnetic resonance assessment of iron overload by separate measurement of tissue ferritin and hemosiderin iron Predicting pituitary iron and endocrine dysfunction
Better survival and less cardiac morbidity in female patients with thalassemia major: a review of the literature. A preclinical approach for gene therapy of [beta]-thalassemia
The role of reduced intensity preparative regimens in patients with thalassemia given hematopoietic transplantation
Progress in hematopoietic stem cell transplantation as allogeneic cellular gene therapy in thalassemia
Emerging insights in the management of hemoglobin E beta thalassemia
Fetal globin gene inducers: novel agents and new potential
Detection of the cardiovascular complications of thalassemia by echocardiography
Cardiovascular MRI in thalassemia major
Complexity of alpha thalassemia: growing health problem with new approaches to screening, diagnosis, and therapy
Nutritional deficiencies in patients with thalassemia
Ferritin iron minerals are chelator targets, antioxidants, and coated, dietary iron
Pulmonary hypertension in thalassemia
The natural history of thalassemia intermedia
Hepcidin and Hfe in iron overload in [beta]-thalassemia
Fertility potential in thalassemia major women: current findings and future diagnostic tools
Redefining thalassemia as a hypercoagulable state
Treatment options for thalassemia patients with osteoporosis
Health care transition in thalassemia: pediatric to adult-oriented care
Ninth Cooley's Anemia Symposium: summary and perspective.
Clinical trials in thalassemia: insights from the patient community
Pathogenesis and management of iron toxicity in thalassemia
The role of antioxidants and iron chelators in the treatment of oxidative stress in thalassemia
Thalassemia as a global health problem: recent progress toward its control in the developing countries
Iron metabolism and ineffective erythropoiesis in β-thalassemia mouse models
Hepcidin in β-thalassemia
Therapy for β-globinopathies: a brief review and determinants for successful and safe correction
Humanized mouse models of Cooley's anemia: correct fetal-to-adult hemoglobin switching, disease onset, and disease pathology
Strategy for a multicenter phase I clinical trial to evaluate globin gene transfer in β-thalassemia
Hematopoietic stem cell mobilization strategies for gene therapy of beta thalassemia and sickle cell disease
Transcriptional silencing of fetal hemoglobin by BCL11A
The challenge of obtaining therapeutic levels of genetically modified hematopoietic stem cells in β-thalassemia patients
Deferiprone
Combined iron chelation therapy
Deferasirox: current knowledge and future challenges
Monitoring the efficiency of iron chelation therapy: the potential of nontransferrin-bound iron
Critical appraisal of growth retardation and pubertal disturbances in thalassemia
Magnetic resonance assessment of iron overload by separate measurement of tissue ferritin and hemosiderin iron
Predicting pituitary iron and endocrine dysfunction
Better survival and less cardiac morbidity in female patients with thalassemia major: a review of the literature.
A preclinical approach for gene therapy of β-thalassemia
The role of reduced intensity preparative regimens in patients with thalassemia given hematopoietic transplantation
Progress in hematopoietic stem cell transplantation as allogeneic cellular gene therapy in thalassemia
Emerging insights in the management of hemoglobin E beta thalassemia
Fetal globin gene inducers: novel agents and new potential
Detection of the cardiovascular complications of thalassemia by echocardiography
Cardiovascular MRI in thalassemia major
Complexity of alpha thalassemia: growing health problem with new approaches to screening, diagnosis, and therapy
Nutritional deficiencies in patients with thalassemia
Ferritin iron minerals are chelator targets, antioxidants, and coated, dietary iron
Pulmonary hypertension in thalassemia
The natural history of thalassemia intermedia
Hepcidin and Hfe in iron overload in β-thalassemia
Fertility potential in thalassemia major women: current findings and future diagnostic tools
Redefining thalassemia as a hypercoagulable state
Treatment options for thalassemia patients with osteoporosis
Health care transition in thalassemia: pediatric to adult-oriented care
Ninth Cooley's Anemia Symposium: summary and perspective
| Erscheint lt. Verlag | 24.9.2010 |
|---|---|
| Reihe/Serie | Annals of the New York Academy of Sciences |
| Verlagsort | Hoboken |
| Sprache | englisch |
| Maße | 178 x 255 mm |
| Gewicht | 562 g |
| Themenwelt | Medizinische Fachgebiete ► Innere Medizin ► Hämatologie |
| Schlagworte | Hämatologie |
| ISBN-10 | 1-57331-782-9 / 1573317829 |
| ISBN-13 | 978-1-57331-782-5 / 9781573317825 |
| Zustand | Neuware |
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