Nerve Growth Factor & Pain

Paola Sarchielli (Autor)

Buch | Softcover

69 Seiten

2011
Nova Science Publishers Inc (Verlag)
978-1-61668-264-4 (ISBN)

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Nerve growth factor (NGF) has a key role not only in the development of sensory and autonomic neurons, but also in the processes of nociception. This book examines the evidence of the involvement of NGF in painful diseases, and suggests the potential usefulness of anti-NGF strategies as novel analgesics for the disabling pathological conditions.

Nerve growth factor (NGF) has a key role not only in the development of sensory and autonomic neurons, but also in the processes of nociception. Several central and peripheral mechanisms have been postulated as the basis of effects of NGF in nociceptive pathways. It has been implicated both in inflammatory and neuropathic pain mechanisms and strategies against NGF, its receptors, and down-stream intracellular signalling activated by this neurotrophin (NT) have been proposed for the treatment of these pathological conditions. This book examines recent evidence of the involvement of NGF in painful diseases and suggests the potential usefulness of anti-NGF strategies as novel analgesics for these disabling pathological conditions.

Introduction; NGF & nociception; Intracellular mechanisms of NGF action; Pathophysiological mechanisms of inflammatory & neuropathic pain; Experimental evidence for the involvement of NGF in inflammatory & neuropathic pain; Pathophysiological mechanisms of migraine; Pathophysiology of fibromyalgia; Involvement of NGF in the pathophysiological mechanisms of migraine & fibromyalgia; Index

Verlagsort	New York
Sprache	englisch
Maße	230 x 155 mm
Gewicht	142 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Schmerztherapie
ISBN-10	1-61668-264-7 / 1616682647
ISBN-13	978-1-61668-264-4 / 9781616682644
Zustand	Neuware