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Cell Migration: Signalling and Mechanisms

F. Entschladen, K.S. Zänker (Herausgeber)

Buch | Hardcover

176 Seiten

2009
Karger, S (Verlag)
978-3-8055-9321-2 (ISBN)

Lese- und Medienproben

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Cell migration is a highly complex process which involves several compartments of the cell, including surface receptors, signalling elements and the cytoskeleton. It plays an essential role in embryogenesis, wound healing and inflammatory responses, and a dysregulation of cell movement can cause pathological states such as developmental defects, chronic inflammation, cancer invasion and metastasis. Covering extracellular regulatory signals and intracellular signal transduction pathways as well as the molecular mechanisms of migration in stem cells, leukocytes and tumor cells in the adult human organism, this book summarizes the current state of knowledge about cell migration. In the first part, the major aspects of different migratory cells in health and disease are covered, with special emphasis on T lymphocytes. The second part provides a comprehensive overview of the principal molecular mechanisms of migration such as adhesion receptors, cytoskeletal rearrangements and locomotor force generation, which, together, can be referred to as a cell’s ‘migrosome’. With contributions by eminent international scientists from different disciplines this book will serve as a valuable resource not only for researchers in cell biology, immunology and oncology, but also for clinicians who wish to learn more about the role of migratory processes in health and disease.

Erscheint lt. Verlag	29.12.2009
Reihe/Serie	Translational Research in Biomedicine
Mitarbeit	Herausgeber (Serie): S.H.H. Chan
Zusatzinfo	20 fig., 2 tab.
Verlagsort	Basel
Sprache	englisch
Gewicht	688 g
Themenwelt	Medizin / Pharmazie ► Studium
Schlagworte	Cell Biology • Hardcover, Softcover / Medizin/Nichtklinische Fächer • immunology • Molecular Biology • Oncology • Zelle (biolog.) • Zelle (Biologie)
ISBN-10	3-8055-9321-X / 380559321X
ISBN-13	978-3-8055-9321-2 / 9783805593212
Zustand	Neuware