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Cystic Fibrosis -

Cystic Fibrosis

Etiology, Diagnosis & Treatments

Paul N Leatte (Herausgeber)

Buch | Hardcover
275 Seiten
2010
Nova Science Publishers Inc (Verlag)
978-1-60741-833-7 (ISBN)
CHF 318,45 inkl. MwSt
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Cystic Fibrosis is a hereditary disease affecting the exocrine (mucus) glands of the lungs, liver, pancreas, and intestines, causing progressive disability due to multisystem failure. Individuals with CF can be diagnosed prior to birth by genetic testing. There is no known cure for CF. This book presents research in this field.
Cystic Fibrosis (also known as CF, mucovoidosis, or mucoviscidosis) is a hereditary disease affecting the exocrine (mucus) glands of the lungs, liver, pancreas, and intestines, causing progressive disability due to multisystem failure. Abnormally thick mucus results in frequent lung infections. Diminished secretion of pancreatic enzymes is the main cause of poor growth, greasy stools, and deficiency in fat-soluble vitamins. Males can be infertile due to the condition congenital bilateral absence of the vas deferens. Often, symptoms of CF appear in infancy and childhood. Meconium ileus is a typical finding in new-born babies with CF.Individuals with CF can be diagnosed prior to birth by genetic testing. New-born screening tests are increasingly common and effective(although false positives may occur, and children need to be brought in for a sweat test to distinguish disease vs carrier status). The diagnosis of CF may be confirmed if high levels of salt are found during a sweat test, although some false positives may occur.There is no known cure for CF. This book presents important research in the field.

Preface; Newborn screening for cystic fibrosis; Cystic fibrosis and respiratory viral infections; Cystic fibrosis, pseudomonas aeruginosa infection, and relevance of innate immune response: challenge for hematopoietic stem cell transplantation; Neutrophil elastase-mediated modulation of pathophysiology in cystic fibrosis lung disease; Genotypic hetereogeneity of the molecular basis of cystic fibrosis: the paradigm of lithuanian population genetic testing; Serum transferrin microheterogeneity in cystic fibrosis; Effects of the lack of transport of thiocyanate in cystic fibrosis lung disease; Treatments for cystic fibrosis: the role of adherence, importance and burden; Cystic Fibrosis -- update on diagnosis and treatment; How effective are nutritional interventions in children and adults with cystic fibrosis?; Sweat test: recommendations for good practice and analytical criteria of the methods used; New trends in the inhibition of Pseudomonas aeruginosa quorum sensing activity; Ocular surface changes in patients with cystic fibrosis; Pseudo-Bartter Syndrome in cystic fibrosis; Management of cystic fibrosis-related arthritis; Cumbria Medicines for Children Research; Index.

Erscheint lt. Verlag 24.3.2010
Zusatzinfo Illustrations
Verlagsort New York
Sprache englisch
Maße 260 x 180 mm
Gewicht 732 g
Themenwelt Medizinische Fachgebiete Innere Medizin Gastroenterologie
ISBN-10 1-60741-833-9 / 1607418339
ISBN-13 978-1-60741-833-7 / 9781607418337
Zustand Neuware
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