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Handbook of Statistical Genetics 2V Set 2e

DJ Balding (Autor)

Software / Digital Media
1308 Seiten
2006
John Wiley & Sons Ltd (Hersteller)
978-0-470-02262-7 (ISBN)
CHF 459,95 inkl. MwSt
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This new edition contains nine new articles, including recent developments in gene-expression data analysis. The existing articles have been fully updated, where necessary, and all the references have been updated. * Comprehensive coverage of a thriving area of research. * Features nine newly commissioned chapters.
From the Reviews of the First Edition: "This magnificent book attempts to catalogue and introduce all aspects of modern statistical genetics...I can thoroughly recommend it." Short Book Reviews of ISI "...extremely well written and referenced work, which must come highly recommended..." Statistical Methods in Medical Research* Provides comprehensive coverage of a thriving area of research* Features nine newly commissioned chapters* All existing chapters have been fully updated with new advances in the field and new references* Now includes a glossary of terms, and a list of acronyms and abbreviations.* Features extensive cross-referencing between chapters.* Each chapter is written by a leading international authority from the field.* Complemented by examples, case studies, and references to useful resources on the web.

D. J. Balding has been one of the most prolific and influential authors of the last decade in the field of statistical interpretation of forensic DNA evidence. M. Bishop, UK HGMP Resource Centre, Cambridge, UK.

PART I: SEQUENCE, STRUCTURE AND EXPRESSION. Chromosome Maps. Statistical Significance in Biological Sequence Comparison. Bayesian Methods in Genomics. Statistical Approaches in Eukaryotic Gene Prediction. Comparative Genomics. Gene-Expression 1. Protein Structure. Probabilistic Models for the Study of Protein Evolution. PART II: EVOLUTIONARY GENETICS. Adaptive Molecular Evolution. Genome Evolution. Virus Evolution. Application of the Likelihood Function in Phylogenetic Analysis. Phylogenetics: Parsimony and Distance Methods. Evolutionary Quantitative Genetics. PART III: ANIMAL AND PLANT BREEDING. QTLs in Inbred Lines. Mapping Quantitative Trait Loci in Outbred Pedigrees. Inferences about Breeding Values. Marker Assisted Selection and Introgression. PART IV: POPULATION GENETICS. Mathematical Models in Population Genetics. Coalescent Theory. Inference Under the Coalescent. Linkage Disequilibrium and Recombination. Inferences from Spatial Population Genetics. Analysis of Population Subdivision. Conservation Genetics. Genetic History of the Human Species. Forensics. PART V: GENETIC EPIDEMIOLOGY. Introduction to Genetic Epidemiology. Statistical Basis of Risk Calculations: A Status Report. Linkage Analysis. Nonparametric Linkage. Population Association. The Transmission/Disequilibrium Test. Pharmacogenetics. PART VI: APPLICATIONS. Ethics in the Use of Statistics in Genetics

Erscheint lt. Verlag 31.3.2006
Verlagsort Chichester
Sprache englisch
Maße 201 x 259 mm
Gewicht 2790 g
Themenwelt Mathematik / Informatik Mathematik Statistik
Naturwissenschaften Biologie Genetik / Molekularbiologie
ISBN-10 0-470-02262-0 / 0470022620
ISBN-13 978-0-470-02262-7 / 9780470022627
Zustand Neuware
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