Pulmonomics: Omics Approaches for Understanding Pulmonary Diseases

Sudipto Saha, Sreyashi Majumdar, Parthasarathi Bhattacharyya (Autoren)

Buch | Hardcover

405 Seiten

2023 | 1st ed. 2023
Springer Verlag, Singapore
978-981-99-3504-8 (ISBN)

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This book comprehensively reviews various omics approaches like genomics, proteomics, transcriptomics, and metabolomics for understanding pulmonary disease at molecular and systems levels. The initial chapters present the pathogenesis of major pulmonary diseases, namely, obstructive diseases, restrictive diseases, vascular diseases, infectious diseases, and neoplastic carcinoma. The book chapters provide current information about the role of the microbiome and applications of medical imaging, bioinformatics tools, and databases for diagnosis and designing treatment strategies against complex lung diseases. Further, the book discusses omics technologies to identify biomarkers for the early diagnosis and prognosis of pulmonary diseases. Finally, the book elucidates the multi-omics approaches and data integration using mathematical modeling for insights into the disease etiology towards improving the prognostics and predictive accuracy of disease phenotypes.

Dr. Sudipto Saha is an Associate Professor at the Division of Bioinformatics, Bose Institute, Kolkata, India. He joined Bose Institute as a DBT-Ramalingaswami fellow in 2012. He has earlier worked as a postdoctoral research fellow at Indiana University, School of Informatics, Indianapolis, USA (2007-2008) and at Case Western Reserve University, School of Medicine, Cleveland, USA (2008-20012). He did his Ph.D. (Bioinformatics) in 2007 from Jawaharlal Nehru University (work done at CSIR-Institute of Microbial Technology, Chandigarh). His research interests are in pulmonary diseases like asthma/COPD and tuberculosis, and has a specialization in bioinformatics and OMICS data analysis. He has more than 22 years of research experience in Immunoinformatics, Proteomics, Bioinformatics, and Machine Learning Techniques. He has published more than 85 research articles in peer-reviewed international journals and authored several book chapters. Dr. Sreyashi Majumdar has obtained her Ph.D. degree from the University of Calcutta, Kolkata, India (2022). She pursued her PhD research at Bioinformatics Centre, Bose Institute, Kolkata, India under the guidance of Dr. Sudipto Saha. Her research interest encompasses the systemic discovery of asthma biomarkers for therapeutics. She has published several research articles in peer-reviewed international journals and has also authored a book chapter. She has several awards accredited to her. Dr. Parthasarathi Bhattacharyya did his post-doctoral fellowship in pulmonary medicine from PGIMER, Chandigarh and presently working as the lead pulmonologist attached to the Institute of Pulmocare and Research, Kolkata, India. He has been engaged to serve the motto of the institute as research, education, and patient care for over two decades. He keeps a keen interest in research, teaching, and innovative work. He has published more than 75 research articles in peer-reviewed national and international journals

Chapter 1_Introduction to Pulmonary Diseases and OMICS approaches.- Chapter 2_Obstructive Pulmonary Diseases.- Chapter 3_COPD (Chronic Obstructive Pulmonar Diseases).- Chapter 4_ Asthma.- Chapter 5_Other obstructive airway diseases like Bronchiectases, Focal airway narrowing.- Chapter 6_Restrictive Pulmonary Diseases (Common qualities and features with examples).- Chapter 7_Interstitial Pulmonary fibrosis (IPF).- Chapter 8_Sarcoidosis.- Chapter 9_ Other restrictive airway diseases like pneumonitis, pleural thickening.- Chapter 10_Vascular Diseases.- Chapter 11_Pulmonary hypertension.- Chapter 12_Pulmonary edema.- Chapter 13_ Other vascular diseases like Pulmonary Edema, Cor Pulmonale.- Chapter 14_Infectious Diseases.- Chapter 15_Tuberculosis.- Chapter 16_Cystic fibrosis.- Chapter 17_Pneumonia, COVID-19 and others.- Chapter 18_Neoplastic Diseases/Lung Cancer.

Erscheinungsdatum	02.11.2023
Zusatzinfo	1 Illustrations, black and white; XIII, 405 p. 1 illus.
Verlagsort	Singapore
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Informatik ► Weitere Themen ► Bioinformatik
	Medizin / Pharmazie ► Studium
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
Schlagworte	Bioinformatics • Biomarkers • genomics • Imaging • Proteomics • Pulmonary Diseases
ISBN-10	981-99-3504-0 / 9819935040
ISBN-13	978-981-99-3504-8 / 9789819935048
Zustand	Neuware