Two-Dimensional Liquid Chromatography

Principles and Practical Applications

Oliver Jones (Autor)

Buch | Softcover

75 Seiten

2020 | 1st ed. 2020
Springer Verlag, Singapore
978-981-15-6189-4 (ISBN)

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This book addresses the growing interest in the field of two-dimensional liquid chromatography (2DLC), a powerful approach to increasing resolution, available peak capacity, and selectivity in analytical chromatography. 2DLC is suitable for many applications, including in the pharmaceutical and polymer industries and the omic sciences (metabolomics, lipidomics and proteomics). Thanks to recent advances in technology and software the instrumentation needed to perform 2D-LC is broadly available to the analytical community in both industry and academia. Indeed, the technique can now be considered ready for application in R&D as well as in QA and QC labs, yet it is not widely known about outside academic laboratories and is rarely taught at the undergraduate level. This book outlines the main principles and features of 2D-LC (including comprehensive and heart-cutting modes, method development and real world applications) to enable modern analysts to start using this fascinating technique.The book offers an ideal starting point for those wishing to get into 2D-LC and will also be of interest to more experienced scientists in the field.

Oliver Jones is an analytical chemist based at RMIT University in Melbourne, where he serves as an full Professor and Associate Dean. Originally from Manchester in the UK, Oliver was awarded a B.Sc. (Honours) from Queen Mary University of London and obtained his M.Sc. and Ph.D. from Imperial College London. He then held a Postdoctoral Fellowship at the University of Cambridge. Oliver left Cambridge to take up a lectureship at the University of Durham before moving to RMIT in 2012.Oliver’s group conducts research in analytical methods and technologies, predominantly in multidimensional chromatography and NMR, for a range of applications, particularly metabolomics and the trace analysis of environmental pollutants. Oliver also has a passion for teaching and recently helped develop a mobile game app called “Chirality-2” to help teach organic chemistry. He is currently a member of the Australian Academy of Science National Committee for Chemistry.

Introduction to 2DLC .- Basic Principles.- Method development.- Data Analysis.- Hyphenation.- Applications of 2D-LC.- Conclusions and Future Developments.- Further Reading.

Erscheinungsdatum	30.07.2020
Reihe/Serie	SpringerBriefs in Molecular Science
Zusatzinfo	18 Illustrations, color; 2 Illustrations, black and white; XVI, 75 p. 20 illus., 18 illus. in color.
Verlagsort	Singapore
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Mathematik / Informatik ► Informatik ► Theorie / Studium
	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Zellbiologie
	Naturwissenschaften ► Chemie ► Analytische Chemie
Schlagworte	2D-LC analysis • Capillary electrophoresis • Liquid Chromatography Column Selection • Mass Transfer Effects • Metabolomics Liquid Chromatography • Multiple Heart-Cutting Sampling • Peak Capacity • Proteomics Liquid Chromatography • separation science • Two-Dimensional Liquid Chromatography (2D-LC)
ISBN-10	981-15-6189-3 / 9811561893
ISBN-13	978-981-15-6189-4 / 9789811561894
Zustand	Neuware