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Moving Boundary PDE Analysis - William Schiesser

Moving Boundary PDE Analysis

Biomedical Applications in R
Buch | Hardcover
182 Seiten
2019
CRC Press (Verlag)
978-0-367-22483-7 (ISBN)
CHF 189,95 inkl. MwSt
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The book is directed to the numerical integration (solution) of systems of partial differential equations (PDEs) for which the boundary conditions move in space. In applications, the physical boundaries move as the solution evolves in time. The book provides examples of the applications in tumor growth and atherosclerosis
Mathematical models stated as systems of partial differential equations (PDEs) are broadly used in biology, chemistry, physics and medicine (physiology). These models describe the spatial and temporial variations of the problem system dependent variables, such as temperature, chemical and biochemical concentrations and cell densities, as a function of space and time (spatiotemporal distributions).

For a complete PDE model, initial conditions (ICs) specifying how the problem system starts and boundary conditions (BCs) specifying how the system is defined at its spatial boundaries, must also be included for a well-posed PDE model. In this book, PDE models are considered for which the physical boundaries move with time. For example, as a tumor grows, its boundary moves outward. In atherosclerosis, the plaque formation on the arterial wall moves inward, thereby restricting blood flow with serious consequences such as stroke and myocardial infarction (heart attack).

These two examples are considered as applications of the reported moving boundary PDE (MBPDE) numerical method (algorithm). The method is programmed in a set of documented routines coded in R, a quality, open-source scientific programming system. The routines are provided as a download so that the reader/analyst/researcher can use MFPDE models without having to first study numerical methods and computer programming.

William E. Schiesser, emeritus professor at Lehigh University. Schiesser is the Emeritus McCann Professor in the chemical and biomolecular engineering department as well as a former professor in the mathematics department. recently authored several books on computer-based solutions to model real-life phenomena, such as the development of Parkinson’s disease.Schiesser holds a Ph.D. from Princeton University and an honorary Sc.D. from the University of Mons, Belgium. He is the author or co-author of numerous books in his field of research on numerical methods and associated software for ordinary, differential-algebraic and partial differential equations (ODE/DAE/PDEs) and the development of mathematical models based on ODE/DAE/PDEs.

1. PDE Model Formulation. 2. PDE Model Implementation. 3. PDE Model Output. 4. Tumor growth. 5. Plaque Formation in Atherosclerosis. Appendix A1. Test of Spline Regridding. Appendix A2. Test of Moving Boundary Algorithm Spline Formulation. Appendix A3. Test of Moving Boundary Algorithm Finite Difference Formulation.

Erscheinungsdatum
Zusatzinfo 22 Tables, black and white; 86 Illustrations, black and white
Verlagsort London
Sprache englisch
Maße 156 x 234 mm
Gewicht 335 g
Themenwelt Mathematik / Informatik Mathematik Analysis
Mathematik / Informatik Mathematik Angewandte Mathematik
Medizin / Pharmazie Physiotherapie / Ergotherapie Orthopädie
Studium 1. Studienabschnitt (Vorklinik) Physiologie
Technik Medizintechnik
ISBN-10 0-367-22483-6 / 0367224836
ISBN-13 978-0-367-22483-7 / 9780367224837
Zustand Neuware
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