Hidden Markov Models

Methods and Protocols

David R. Westhead, M. S. Vijayabaskar (Herausgeber)

Buch | Softcover

221 Seiten

2018 | Softcover reprint of the original 1st ed. 2017
Humana Press Inc. (Verlag)
978-1-4939-8292-9 (ISBN)

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This volume aims to provide a new perspective on the broader usage of Hidden Markov Models (HMMs) in biology. Hidden Markov Models: Methods and Protocols guides readers through chapters on biological systems; ranging from single biomolecule, cellular level, and to organism level and the use of HMMs in unravelling the complex mechanisms that govern these complex systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Hidden Markov Models: Methods and Protocols aims to demonstrate the impact of HMM in biology and inspire new research.

Introduction to Hidden Markov Models and its Applications in Biology.- HMMs in Protein Fold Classification.- Application of Hidden Markov Models in Biomolecular Simulations.- Predicting Beta Barrel Transmembrane Proteins using HMMs.- Predicting Alpha Helical Transmembrane Proteins using HMMs.- Self-Organizing Hidden Markov Model Map (SOHMMM): Biological Sequence Clustering and Cluster Visualization.- Analyzing Single Molecule FRET Trajectories using HMM.- Modelling ChIP-seq Data using HMMs.- Hidden Markov Models in Bioinformatics: SNV Inference from Next Generation Sequence.- Computationally Tractable Multivariate HMM in Genome-wide Mapping Studies.- Hidden Markov Models in Population Genomics.- Differential Gene Expression (DEX) and Alternative Splicing Events (ASE) for Temporal Dynamic Processes using HMMs and Hierarchical Bayesian Modeling Approaches.- Finding RNA-Protein Interaction Sites using HMM.- Automated Estimation of Mouse Social Behaviours Based on a Hidden Markov Model.- Modeling Movement Primitives with Hidden Markov Models for Robotic and Biomedical Applications.

Erscheinungsdatum	18.08.2018
Reihe/Serie	Methods in Molecular Biology ; 1552
Zusatzinfo	17 Illustrations, color; 42 Illustrations, black and white; X, 221 p. 59 illus., 17 illus. in color.
Verlagsort	Totowa, NJ
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Mathematik / Informatik ► Informatik ► Theorie / Studium
	Informatik ► Weitere Themen ► Bioinformatik
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
Schlagworte	Biological system • cellular level • DNA/RNA biomolecules • HMM • organism level • Protein • single biomolecule
ISBN-10	1-4939-8292-3 / 1493982923
ISBN-13	978-1-4939-8292-9 / 9781493982929
Zustand	Neuware