Multistate Stochastic Models for Data Analysis
Crc Press Inc (Verlag)
978-1-4665-5759-8 (ISBN)
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Section I Introduction: Principles and Fundamentals of RNA Nanotechnology
The Emerging Field of RNA Nanotechnology
Peixuan Guo
Uniqueness, Advantages, Challenges, Solutions, and Perspectives in Therapeutics Applying RNA Nanotechnology
Peixuan Guo, Farzin Haque, Brent Hallahan, Randall Reif, Hui Li, and Shaoying Wang
Section II RNA Folding, Structure, and Motifs in RNA Nanoparticle Assembly
Kink Turn Structural Motif in RNA
Peter Daldrop, Lin Huang, Kersten T. Schroeder, Jia Wang, and David M. J. Lilley
RNA Nanotechnology: Learning from Biologically Active RNA Nanomachines
Neocles B. Leontis and Emil F. Khisamutdinov
Natural Selection and Structural Polymorphism of RNA 3D Structures Involving GNRA Loops and Their Receptor Motifs
Takahiro Tanaka, Hiroyuki Furuta, and Yoshiya Ikawa
RNA Junction Motifs as Scaffolds for Construction of Multifunctional RNA Nanoparticles
Farzin Haque and Peixuan Guo
Section III RNA Computation and Structure Prediction for RNA Nanoparticle Construction
Role of Dynamics in RNA Nanostructure Design
Wojciech Kasprzak and Bruce A. Shapiro
RNA Three-Dimensional Structure Determination Using Experimental Constraints
Feng Ding and Nikolay V. Dokholyan
Section IV RNA Chemistry for Nanoparticle Synthesis, Conjugation, and Labeling
Nucleotide Chemistry for RNA Nanoparticle Labeling, Conjugation, and Synthesis
Brian M. Laing and Donald E. Bergstrom
RNA Conjugations and Ligations for RNA Nanotechnology
Eduardo Paredes and Subha R. Das
Atom-Specific Mutagenesis of RNAs for Structure, Function, and Therapeutics Studies
Huiyan Sun and Zhen Huang
Section V Single-Molecule and Biophysical Techniques in RNA Nanostructure Analysis
Atomic Force Microscopy of RNA: Imaging and Beyond
Peter M. Schoen, Luda S. Shlyakhtenko, and Yuri L. Lyubchenko
Single-Molecule Approach to Study RNA Nanoparticles
Hui Zhang, Chris Richards, Zhengyi Zhao, and Peixuan Guo
Section VI Methods for the Assembly of RNA Nanoparticles
Fabrication Methods for RNA Nanoparticle Assembly Based on Bacteriophage phi29 Packaging RNA Structural Features
Yi Shu, Bahar Seremi, and Peixuan Guo
Synthetic RNA-Protein Nanostructures and Their Potential Applications
Hirohisa Ohno, Eriko Osada, Tan Inoue, and Hirohide Saito
DNA Nanotechnology as Reference for RNA Nanotechnology
Zhen-Gang Wang and Baoquan Ding
Section VII RNA Nanoparticles for Therapy of Cancer, Viral Infections, and Genetic Diseases
Thermodynamically Stable RNA Three-Way Junction for Constructing Multifunctional Nanoparticles for Delivery of Therapeutics
Dan Shu, Yi Shu, Farzin Haque, Sherine Abdelmawla, and Peixuan Guo
Design and Construction of RNA Nanoparticles Targeting Prostate Cancer
Randall Reif and Peixuan Guo
Conjugation of RNA Aptamer to RNA Nanoparticles for Targeted Drug Delivery
Katherine Germer, Fengmei Pi, Peixuan Guo, and Xiaoting Zhang
Extracellular Membrane Vesicles and Extracellular Membrane Vesicle-Based Therapeutics for Brain Diseases
Jayden A. Smith, Clara Alfaro-Cervello, Chiara Cossetti, Nunzio Iraci, Matilde Stefanini, and Stefano Pluchino
Pharmacokinetics and Pharmacodynamics of RNA Nanoparticles
Markos Leggas
Section VIII RNA Nanotechnology for Diagnostic Applications
RNA Nanotechnology in Sensing, Detection, and Disease Diagnosis
Ping Lei and Guanxin Shen
Potentials of RNA Aptamers for Viral Detection and Treatment
Longxin Chen, Runting Li, and Runlin Z. Ma
Section IX Application of RNA Aptamers in RNA Nanotechnology and Therapeutics
Application of RNA Aptamers in Nanotechnology and Therapeutics
Hua Shi
Aptamers Targeting a Subunit or a Conformation of Glutamate Ion Channel Receptors
Zhen Huang, William Jaremko, Chi-yen Lin, and Li Niu
Section X Application of miRNAs in RNA Nanotechnology and Therapeutics
Application of MicroRNAs in RNA Nanotechnology and Antiviral Therapeutics
Ye Qiu, Xin Ye, Maged Hemida, Mary Zhang, Paul Hanson, and Decheng Yang
MicroRNAs: Biology and Role in RNA Nanotechnology
Bin Guo and Daniel W. Binzel
Section XI Application of siRNAs in RNA Nanotechnology and Therapeutics
Current Advances in Self-Assembly RNAi Nanoparticles
Ka-To Shum, Jiehua Zhou, and John J. Rossi
Self-Assembly of siRNA Containing Nanoparticles
Mengyao Zheng, Thomas Kissel, and Olivia M. Merkel
Index
| Erscheint lt. Verlag | 1.1.2021 |
|---|---|
| Zusatzinfo | 50 Illustrations, black and white |
| Verlagsort | Bosa Roca |
| Sprache | englisch |
| Maße | 156 x 235 mm |
| Themenwelt | Mathematik / Informatik ► Mathematik |
| Studium ► Querschnittsbereiche ► Epidemiologie / Med. Biometrie | |
| ISBN-10 | 1-4665-5759-1 / 1466557591 |
| ISBN-13 | 978-1-4665-5759-8 / 9781466557598 |
| Zustand | Neuware |
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