Immuno Systems Biology

A macroscopic approach for immune cell signaling

Kumar Selvarajoo (Autor)

Buch | Softcover

146 Seiten

2016 | Softcover reprint of the original 1st ed. 2013
Springer-Verlag New York Inc.
978-1-4939-5090-4 (ISBN)

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Immuno Systems Biology aims to study the immune system in the more integrated manner on how cells and molecules participate at different system levels to the immune function. Through this book Kumar Selvarajoo introduces to physicists, chemists, computer scientists, biologists and immunologists the idea of an integrated approach to the understanding of mammalian immune system. Geared towards a researcher with limited immunological and computational analytical experience, the book provides a broad overview to the subject and some instruction in basic computational, theoretical and experimental approaches. The book links complex immunological processes with computational analysis and emphasizes the importance of immunology to the mammalian system.

Preface.- Systems biology of population cell response.- Perturbation-response approach for biological network analysis.- Basics of the mammalian immune system.- Inferring novel features of the TLR4 pathways.- Signaling Flux Redistribution.- Investigating the TLR3 signaling dynamics.- Understanding TNFR1 signaling dynamics.- TRAIL signaling in cancer.- Stochasticity and variability: insights from single cell dynamics.- Investigating single cell stochasticity in TRAIL signaling.- The distinction between single cell and population dynamics.- Finding chaos in biology.- Concluding remarks.- Index.

Erscheinungsdatum	04.10.2016
Reihe/Serie	Systems Biology ; 3
Zusatzinfo	61 Illustrations, color; 8 Illustrations, black and white; IX, 146 p. 69 illus., 61 illus. in color.
Verlagsort	New York
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Mathematik / Informatik ► Informatik ► Theorie / Studium
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
	Naturwissenschaften ► Biologie ► Zellbiologie
Schlagworte	currentjoe
ISBN-10	1-4939-5090-8 / 1493950908
ISBN-13	978-1-4939-5090-4 / 9781493950904
Zustand	Neuware