Bioinformatics

Volume I: Data, Sequence Analysis, and Evolution

Buch | Hardcover

491 Seiten

2016 | 2nd ed. 2017
Humana Press Inc. (Verlag)
978-1-4939-6620-2 (ISBN)

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This second edition provides updated and expanded chapters covering a broad sampling of useful and current methods in the rapidly developing and expanding field of bioinformatics. Bioinformatics, Volume I: Data, Sequence Analysis, and Evolution, Second Edition is comprised of three sections: Data and Databases, Sequence Analysis, and Phylogenetics and Evolution. The first section details bioinformatics methodologies in the generation of sequence and structural data and its organization into conceptual categories, and databases to facilitate further analyses. The Sequence Analysis section describes the fundamental methodologies for processing the sequences of biological molecules: techniques that are used in almost every pipeline of bioinformatics analysis, particularly in the preliminary stages of such pipelines. Last but not least, the phylogenetics and evolution section deals with methodologies that compare biological sequences for the purpose of understanding how they evolved. As a volume in the highly successful Methods in Molecular Biology series, chapters feature the kind of detail and expert implementation advice to ensure positive results.

Comprehensive and practical, Bioinformatics, Volume I: Data, Sequence Analysis, and Evolution, Second Edition is an essential resource for graduate students, early career researchers, and others who are in the process of integrating new bioinformatics methods into their research.

Genome Sequencing.- Sequence Assembly.- A Practical Approach to Protein Crystallography.- Managing Sequence Data.- Genome Annotation.- Working with Ontologies.- The Classification of Protein Domains.- Multiple Sequence Alignment.- Large-Scale Sequence Comparison.- Genomic Database Searching.- Finding Genes in Genome Sequence.- Sequence Segmentation with changeptGUI.- Measuring Natural Selection.- Inferring Trees.- Identifying Optimal Models of Evolution.- Scaling Up the Phylogenetic Detection of Lateral Gene Transfer Events.- Detecting and Analyzing Genetic Recombination Using RDP4.- Species Tree Estimation from Genome-Wide Data with Guenomu.

Erscheinungsdatum	06.01.2017
Reihe/Serie	Methods in Molecular Biology ; 1525
Reihe/Serie	Methods in Molecular Biology ; 1525
Zusatzinfo	81 Illustrations, color; 36 Illustrations, black and white; X, 491 p. 117 illus., 81 illus. in color. With online files/update.
Verlagsort	Totowa, NJ
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Informatik ► Weitere Themen ► Bioinformatik
Themenwelt	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
Schlagworte	Clustering • computational diagnostics • drug discovery • Genotype • Phenotype • phylogenetics and evolution • sequences of biological molecules • systems of interacting elements
ISBN-10	1-4939-6620-0 / 1493966200
ISBN-13	978-1-4939-6620-2 / 9781493966202
Zustand	Neuware