A Primer in Genome Sciences
Sinauer Associates Inc.,U.S. (Verlag)
978-0-87893-234-4 (ISBN)
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This volume bridges the gap between standard genetics textbooks and highly specialised, technical, and advanced treatments of the subdisciplines. It provides an affordable and up-to-date introduction to the field that is suited to advanced undergraduate or early graduate courses. Bioinformatic principles and experimental strategies are explained side-by-side with the experimental methods, establishing a framework that allows teachers to explore topics and the literature at their own pace.
GREG GIBSON, North Carolina State University. - SPENCER MUSE, North Carolina State University.
PART 1: GENOME PROJECTS: ORGANIZATION AND OBJECTIVES - The Human Genome Project - Animal Genome Projects - Plant Genome Projects - Microbial Genome Projects - Boxes - Flat File and Relational Databases - GenBank Files - PART 2: GENOME SEQUENCING AND ANNOTATION - Automated Sequencing - Genome Sequencing - Genome Annotation - Clustering of Gene Families - Boxes - Alignment Algorithms and Tools - BLAST and Alignment Implementation - Hidden Markov Models and Gene Finding - Fundamentals of Phylogenetic Methods - PART 3: GENE EXPRESSION AND THE TRANSCRIPTOME - Parallel Analysis of Gene Expression: Microarrays and Oligonucleotide Arrays SAGE, Microbeads, and Differential Display - Gene-by-Gene Analysis - Properties of Transcriptomes - Boxes - Image Extraction for Microarray Analysis - Clustering Methods - Identification of Regulatory Motifs - PART 4: PROTEOMICS AND FUNCTIONAL GENOMICS - Functional Proteomics - Structural Proteomics - Protein Interaction Maps - High Throughput Forward and Reverse Genetics - Boxes - Domain Profiling - Construction of Transgenic Animals and Plants - PART 5: SNPs AND VARIATION - Single-Nucleotide Polymorphisms - Applications of SNP Technology - SNP Discovery - SNP Genotyping - Boxes - Linkage Disequilibrium Measures - Population-based Association Statistics - Transmission Disequilibrium Test Statistics - PART 6: COMPUTATIONAL GENOMICS - Metabolomics - In silico Genomics
| Erscheint lt. Verlag | 7.1.2002 |
|---|---|
| Zusatzinfo | illustrations |
| Verlagsort | Sunderland |
| Sprache | englisch |
| Maße | 177 x 235 mm |
| Gewicht | 713 g |
| Themenwelt | Informatik ► Weitere Themen ► Bioinformatik |
| Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
| ISBN-10 | 0-87893-234-8 / 0878932348 |
| ISBN-13 | 978-0-87893-234-4 / 9780878932344 |
| Zustand | Neuware |
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